pH-dependent Interactions of the Carboxyl-terminal Helix of Steroidogenic Acute Regulatory Protein with Synthetic Membranes

Steroidogenic acute regulatory (StAR) protein facilitates import of cholesterol into adrenal and gonadal mitochondria where cholesterol is converted to pregnenolone, initiating steroidogenesis. StAR acts exclusively on the outer mitochondrial membrane (OMM) by unknown mechanisms. To identify StAR do...

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Veröffentlicht in:	The Journal of biological chemistry 2005-01, Vol.280 (3), p.2045-2054
Hauptverfasser:	Yaworsky, Dustin C., Baker, Bo Y., Bose, Himangshu S., Best, Katrina B., Jensen, Lauren B., Bell, John D., Baldwin, Michael A., Miller, Walter L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Circular Dichroism Hydrogen-Ion Concentration Hydrolysis Mass Spectrometry Membranes, Artificial Models, Molecular Molecular Sequence Data Phosphoproteins - chemistry Phosphoproteins - metabolism Protein Conformation Recombinant Proteins - chemistry Recombinant Proteins - metabolism
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