Ocular structure and function in an aged monkey with spontaneous diabetes mellitus

Diabetes mellitus develops spontaneously in middle-aged, obese rhesus monkeys, thus making them a good model for examining the effects of co-morbid factors on the development of end-organ damage. Changes in structure and function in the eyes of one monkey who spontaneously developed type 2 diabetes...

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Veröffentlicht in:	Experimental eye research 2005, Vol.80 (1), p.37-42
Hauptverfasser:	Johnson, M.A., Lutty, G.A., McLeod, D.S., Otsuji, T., Flower, R.W., Sandagar, G., Alexander, T., Steidl, S.M., Hansen, B.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Angiography - methods animal model Animals Blood Flow Velocity - physiology Capillaries - pathology choroid Choroid - pathology Choroid - physiopathology diabetes Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - pathology Diabetes Mellitus, Type 2 - physiopathology diabetic retinopathy Diabetic Retinopathy - complications Diabetic Retinopathy - pathology Diabetic Retinopathy - physiopathology Disease Models, Animal Electroretinography - methods Endothelial Cells - pathology Endothelial Cells - physiology Endothelium, Vascular - pathology Endothelium, Vascular - physiopathology Eye - pathology Female Immunohistochemistry - methods Macaca mulatta Ocular Hypertension - complications Ocular Hypertension - pathology Ocular Hypertension - physiopathology Ocular Physiological Phenomena primate retina Retinal Drusen - pathology Retinal Drusen - physiopathology Retinal Hemorrhage - pathology Retinal Hemorrhage - physiopathology Retinal Vessels - pathology Retinal Vessels - physiopathology
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