Intramolecular Carbon Isotopic Composition of Monosodium Glutamate: Biochemical Pathways and Product Source Identification
Monosodium glutamate (MSG) obtained as trade samples from several manufacturers was studied to determine the range of its intramolecular 13C/12C composition. Although the carbon isotopic composition of the total MSG molecule did not differ among manufacturers in most instances, significant differenc...
Gespeichert in:
| Veröffentlicht in: | Journal of agricultural and food chemistry 2005-01, Vol.53 (2), p.197-201 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 201 |
|---|---|
| container_issue | 2 |
| container_start_page | 197 |
| container_title | Journal of agricultural and food chemistry |
| container_volume | 53 |
| creator | Savidge, William B Blair, Neal E |
| description | Monosodium glutamate (MSG) obtained as trade samples from several manufacturers was studied to determine the range of its intramolecular 13C/12C composition. Although the carbon isotopic composition of the total MSG molecule did not differ among manufacturers in most instances, significant differences were observed in the isotopic composition of the α-carboxyl carbon, suggesting that different proprietary strains of industrial microorganisms or MSG purification methods may impart unique isotopic fingerprints upon their products. The 13C depletion of the α-carboxyl carbon relative to the rest of the molecule helps constrain the identity of the potential anapleurotic carboxylating enzymes responsible for its fixation. Keywords: Monosodium glutamate; carbon isotopes; anapleurotic pathway; intramolecular isotope distribution |
| doi_str_mv | 10.1021/jf040200k |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67362650</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>67362650</sourcerecordid><originalsourceid>FETCH-LOGICAL-a471t-fd34fa00da77ce054f8c9370185fec37a7e78be82d2c725f87af2648db6a6b0a3</originalsourceid><addsrcrecordid>eNpt0MFuEzEQBuAVAtFQOPAC4AtIHBbG3rW96Y1G0AYVCEorjtbEa1Onu-tgewU9IHHlNXkSHCVqLpwseT799vxF8ZTCawqMvllbqIEB3NwrJpQzKDmlzf1iAnlYNlzQo-JRjGsAaLiEh8UR5YILUTeT4td8SAF73xk9dhjIDMPKD2QeffIbp8nM9xsfXXL50lvy0Q8--taNPTnrxoQ9JnPy9_cfcuq8vja909iRBabrH3gbCQ4tWQTfjjqRpR-DNmTemiE5m9028nHxwGIXzZP9eVxcvX93OTsvLz6fzWdvL0qsJU2lbavaIkCLUmoDvLaNnlYSaMOt0ZVEaWSzMg1rmZaM20aiZXm9diVQrACr4-LlLncT_PfRxKR6F7XpOhyMH6MSshJMcMjw1Q7q4GMMxqpNcD2GW0VBbbtWd11n-2wfOq560x7kvtwMXuwBxtyLDThoFw9O1JXkYuvKnXMxmZ93cww3249Jri4XS8W-nC7g6_kH9Sn75ztv0Sv8FnLm1ZIBrQCmUjA5PbyMOqp1bn7I7f5nhX8La64l</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>67362650</pqid></control><display><type>article</type><title>Intramolecular Carbon Isotopic Composition of Monosodium Glutamate: Biochemical Pathways and Product Source Identification</title><source>MEDLINE</source><source>American Chemical Society Journals</source><creator>Savidge, William B ; Blair, Neal E</creator><creatorcontrib>Savidge, William B ; Blair, Neal E</creatorcontrib><description>Monosodium glutamate (MSG) obtained as trade samples from several manufacturers was studied to determine the range of its intramolecular 13C/12C composition. Although the carbon isotopic composition of the total MSG molecule did not differ among manufacturers in most instances, significant differences were observed in the isotopic composition of the α-carboxyl carbon, suggesting that different proprietary strains of industrial microorganisms or MSG purification methods may impart unique isotopic fingerprints upon their products. The 13C depletion of the α-carboxyl carbon relative to the rest of the molecule helps constrain the identity of the potential anapleurotic carboxylating enzymes responsible for its fixation. Keywords: Monosodium glutamate; carbon isotopes; anapleurotic pathway; intramolecular isotope distribution</description><identifier>ISSN: 0021-8561</identifier><identifier>EISSN: 1520-5118</identifier><identifier>DOI: 10.1021/jf040200k</identifier><identifier>PMID: 15656648</identifier><identifier>CODEN: JAFCAU</identifier><language>eng</language><publisher>Washington, DC: American Chemical Society</publisher><subject>Bacteria - metabolism ; Biological and medical sciences ; carbon ; Carbon - analysis ; Carbon Isotopes - analysis ; fermentation ; Food additives ; food analysis ; Food industries ; Food Industry ; Fundamental and applied biological sciences. Psychology ; General aspects ; mass spectrometry ; Methods of analysis, processing and quality control, regulation, standards ; monosodium glutamate ; Sodium Glutamate - chemistry ; Sodium Glutamate - isolation & purification ; stable isotopes</subject><ispartof>Journal of agricultural and food chemistry, 2005-01, Vol.53 (2), p.197-201</ispartof><rights>Copyright © 2005 American Chemical Society</rights><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a471t-fd34fa00da77ce054f8c9370185fec37a7e78be82d2c725f87af2648db6a6b0a3</citedby><cites>FETCH-LOGICAL-a471t-fd34fa00da77ce054f8c9370185fec37a7e78be82d2c725f87af2648db6a6b0a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/jf040200k$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/jf040200k$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,780,784,2763,27074,27922,27923,56736,56786</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16437568$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15656648$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Savidge, William B</creatorcontrib><creatorcontrib>Blair, Neal E</creatorcontrib><title>Intramolecular Carbon Isotopic Composition of Monosodium Glutamate: Biochemical Pathways and Product Source Identification</title><title>Journal of agricultural and food chemistry</title><addtitle>J. Agric. Food Chem</addtitle><description>Monosodium glutamate (MSG) obtained as trade samples from several manufacturers was studied to determine the range of its intramolecular 13C/12C composition. Although the carbon isotopic composition of the total MSG molecule did not differ among manufacturers in most instances, significant differences were observed in the isotopic composition of the α-carboxyl carbon, suggesting that different proprietary strains of industrial microorganisms or MSG purification methods may impart unique isotopic fingerprints upon their products. The 13C depletion of the α-carboxyl carbon relative to the rest of the molecule helps constrain the identity of the potential anapleurotic carboxylating enzymes responsible for its fixation. Keywords: Monosodium glutamate; carbon isotopes; anapleurotic pathway; intramolecular isotope distribution</description><subject>Bacteria - metabolism</subject><subject>Biological and medical sciences</subject><subject>carbon</subject><subject>Carbon - analysis</subject><subject>Carbon Isotopes - analysis</subject><subject>fermentation</subject><subject>Food additives</subject><subject>food analysis</subject><subject>Food industries</subject><subject>Food Industry</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General aspects</subject><subject>mass spectrometry</subject><subject>Methods of analysis, processing and quality control, regulation, standards</subject><subject>monosodium glutamate</subject><subject>Sodium Glutamate - chemistry</subject><subject>Sodium Glutamate - isolation & purification</subject><subject>stable isotopes</subject><issn>0021-8561</issn><issn>1520-5118</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpt0MFuEzEQBuAVAtFQOPAC4AtIHBbG3rW96Y1G0AYVCEorjtbEa1Onu-tgewU9IHHlNXkSHCVqLpwseT799vxF8ZTCawqMvllbqIEB3NwrJpQzKDmlzf1iAnlYNlzQo-JRjGsAaLiEh8UR5YILUTeT4td8SAF73xk9dhjIDMPKD2QeffIbp8nM9xsfXXL50lvy0Q8--taNPTnrxoQ9JnPy9_cfcuq8vja909iRBabrH3gbCQ4tWQTfjjqRpR-DNmTemiE5m9028nHxwGIXzZP9eVxcvX93OTsvLz6fzWdvL0qsJU2lbavaIkCLUmoDvLaNnlYSaMOt0ZVEaWSzMg1rmZaM20aiZXm9diVQrACr4-LlLncT_PfRxKR6F7XpOhyMH6MSshJMcMjw1Q7q4GMMxqpNcD2GW0VBbbtWd11n-2wfOq560x7kvtwMXuwBxtyLDThoFw9O1JXkYuvKnXMxmZ93cww3249Jri4XS8W-nC7g6_kH9Sn75ztv0Sv8FnLm1ZIBrQCmUjA5PbyMOqp1bn7I7f5nhX8La64l</recordid><startdate>20050126</startdate><enddate>20050126</enddate><creator>Savidge, William B</creator><creator>Blair, Neal E</creator><general>American Chemical Society</general><scope>FBQ</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20050126</creationdate><title>Intramolecular Carbon Isotopic Composition of Monosodium Glutamate: Biochemical Pathways and Product Source Identification</title><author>Savidge, William B ; Blair, Neal E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a471t-fd34fa00da77ce054f8c9370185fec37a7e78be82d2c725f87af2648db6a6b0a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Bacteria - metabolism</topic><topic>Biological and medical sciences</topic><topic>carbon</topic><topic>Carbon - analysis</topic><topic>Carbon Isotopes - analysis</topic><topic>fermentation</topic><topic>Food additives</topic><topic>food analysis</topic><topic>Food industries</topic><topic>Food Industry</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>General aspects</topic><topic>mass spectrometry</topic><topic>Methods of analysis, processing and quality control, regulation, standards</topic><topic>monosodium glutamate</topic><topic>Sodium Glutamate - chemistry</topic><topic>Sodium Glutamate - isolation & purification</topic><topic>stable isotopes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Savidge, William B</creatorcontrib><creatorcontrib>Blair, Neal E</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of agricultural and food chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Savidge, William B</au><au>Blair, Neal E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intramolecular Carbon Isotopic Composition of Monosodium Glutamate: Biochemical Pathways and Product Source Identification</atitle><jtitle>Journal of agricultural and food chemistry</jtitle><addtitle>J. Agric. Food Chem</addtitle><date>2005-01-26</date><risdate>2005</risdate><volume>53</volume><issue>2</issue><spage>197</spage><epage>201</epage><pages>197-201</pages><issn>0021-8561</issn><eissn>1520-5118</eissn><coden>JAFCAU</coden><abstract>Monosodium glutamate (MSG) obtained as trade samples from several manufacturers was studied to determine the range of its intramolecular 13C/12C composition. Although the carbon isotopic composition of the total MSG molecule did not differ among manufacturers in most instances, significant differences were observed in the isotopic composition of the α-carboxyl carbon, suggesting that different proprietary strains of industrial microorganisms or MSG purification methods may impart unique isotopic fingerprints upon their products. The 13C depletion of the α-carboxyl carbon relative to the rest of the molecule helps constrain the identity of the potential anapleurotic carboxylating enzymes responsible for its fixation. Keywords: Monosodium glutamate; carbon isotopes; anapleurotic pathway; intramolecular isotope distribution</abstract><cop>Washington, DC</cop><pub>American Chemical Society</pub><pmid>15656648</pmid><doi>10.1021/jf040200k</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0021-8561 |
| ispartof | Journal of agricultural and food chemistry, 2005-01, Vol.53 (2), p.197-201 |
| issn | 0021-8561 1520-5118 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67362650 |
| source | MEDLINE; American Chemical Society Journals |
| subjects | Bacteria - metabolism Biological and medical sciences carbon Carbon - analysis Carbon Isotopes - analysis fermentation Food additives food analysis Food industries Food Industry Fundamental and applied biological sciences. Psychology General aspects mass spectrometry Methods of analysis, processing and quality control, regulation, standards monosodium glutamate Sodium Glutamate - chemistry Sodium Glutamate - isolation & purification stable isotopes |
| title | Intramolecular Carbon Isotopic Composition of Monosodium Glutamate: Biochemical Pathways and Product Source Identification |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T13%3A07%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Intramolecular%20Carbon%20Isotopic%20Composition%20of%20Monosodium%20Glutamate:%E2%80%89%20Biochemical%20Pathways%20and%20Product%20Source%20Identification&rft.jtitle=Journal%20of%20agricultural%20and%20food%20chemistry&rft.au=Savidge,%20William%20B&rft.date=2005-01-26&rft.volume=53&rft.issue=2&rft.spage=197&rft.epage=201&rft.pages=197-201&rft.issn=0021-8561&rft.eissn=1520-5118&rft.coden=JAFCAU&rft_id=info:doi/10.1021/jf040200k&rft_dat=%3Cproquest_cross%3E67362650%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=67362650&rft_id=info:pmid/15656648&rfr_iscdi=true |