Prevalence of Mutations and Functional Analyses of Melanocortin 4 Receptor Variants Identified among 750 Men with Juvenile-Onset Obesity

Mutations in the gene encoding the melanocortin 4 receptor (MC4R) are associated with the most common monogenic form of obesity. We examined 750 Danish men with juvenile-onset obesity (body mass index 33.3 ± 2.4 kg/m2) and 706 control subjects (body mass index 21.4 ± 2.1 kg/m2) for mutations in MC4R...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2005-01, Vol.90 (1), p.219-224
Hauptverfasser:	Larsen, Lesli H., Echwald, Søren M., Sørensen, Thorkild I. A., Andersen, Teis, Wulff, Birgitte S., Pedersen, Oluf
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cohort Studies Endocrinopathies Fundamental and applied biological sciences. Psychology Humans Male Medical sciences Mutation Obesity - genetics Receptor, Melanocortin, Type 4 - genetics Receptor, Melanocortin, Type 4 - physiology Vertebrates: endocrinology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!