Heterophilic interactions of platelet factor 4 and RANTES promote monocyte arrest on endothelium

The chemokines platelet factor 4 (PF4) and RANTES (regulated on activation normal T cell expressed and secreted) are secreted by activated platelets and influence multiple cell types and biologic processes. For instance, PF4 inhibits progenitor cell proliferation and angiogenesis, while platelet-der...

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Veröffentlicht in:	Blood 2005-02, Vol.105 (3), p.924-930
Hauptverfasser:	von Hundelshausen, Philipp, Koenen, Rory R., Sack, Markus, Mause, Sebastian F., Adriaens, Wencke, Proudfoot, Amanda E.I., Hackeng, Tilman M., Weber, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Adhesion - physiology Cells, Cultured Chemokine CCL5 - metabolism Chemokines - physiology Endothelium, Vascular - physiology Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunobiology Inflammation Modulation of the immune response (stimulation, suppression) Monocytes - physiology Platelet Factor 4 - metabolism Umbilical Veins
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