Biological and physicochemical properties of gemini quaternary ammonium compounds in which the positions of a cross-linking sulfur in the spacer differ

We synthesized two novel gemini quaternary ammonium compounds (gemini QACs), 4,4′-[1,6-(2,5-dithiahexane)]bis(1-alkylpyridinium bromide) and 4,4′-[1,6-(3,4-dithiahexane)]bis(1-alkylpyridinium bromide), which are essentially two dimerized pyridinium salts. Three gemini QACs in which the positions of...

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Veröffentlicht in:European journal of medicinal chemistry 2005, Vol.40 (1), p.113-123
Hauptverfasser: Shirai, Akihiro, Maeda, Takuya, Nagamune, Hideaki, Matsuki, Hitoshi, Kaneshina, Shoji, Kourai, Hiroki
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Sprache:eng
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