Peripheral nerve schwannoma: two cases exhibiting increased FDG uptake in early and delayed PET imaging

We present two cases of peripheral nerve schwannoma which showed an increased accumulation of 2-deoxy-[(18)F] fluoro-D-glucose (FDG) in the tumors on positron emission tomography (PET) imaging acquired at both 1 h (early phase) and 2 h (delayed phase) after FDG injection. FDG-PET scans were performe...

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Veröffentlicht in:Skeletal radiology 2005-01, Vol.34 (1), p.52-57
Hauptverfasser: HAMADA, Kenichiro, UEDA, Takafumi, HIGUCHI, Ichiro, INOUE, Atsuo, TAMAI, Noriyuki, MYOI, Akira, TOMITA, Yasuhiko, AOZASA, Katsuyuki, YOSHIKAWA, Hideki, HATAZAWA, Jun
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container_title Skeletal radiology
container_volume 34
creator HAMADA, Kenichiro
UEDA, Takafumi
HIGUCHI, Ichiro
INOUE, Atsuo
TAMAI, Noriyuki
MYOI, Akira
TOMITA, Yasuhiko
AOZASA, Katsuyuki
YOSHIKAWA, Hideki
HATAZAWA, Jun
description We present two cases of peripheral nerve schwannoma which showed an increased accumulation of 2-deoxy-[(18)F] fluoro-D-glucose (FDG) in the tumors on positron emission tomography (PET) imaging acquired at both 1 h (early phase) and 2 h (delayed phase) after FDG injection. FDG-PET scans were performed with a dedicated PET scanner (HeadtomeV/ SET2400 W, Shimadzu, Kyoto, Japan) and the PET data analyzed the most metabolically active region of interest (ROI). We set the maximum standardized uptake value (SUV max) with a cut-off point of 3.0 to distinguish benign and malignant lesions. Although the mechanism responsible for the increased FDG uptake in benign schwannomas remains unknown, we discuss our findings in the context of tumor cellularity and briefly review other studies on the subject.
doi_str_mv 10.1007/s00256-004-0845-z
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subjects Adult
Biological and medical sciences
Female
Fluorodeoxyglucose F18
Follow-Up Studies
Head and Neck Neoplasms - diagnostic imaging
Humans
Medical imaging
Medical sciences
Muscle Neoplasms - diagnostic imaging
Neurilemmoma - diagnostic imaging
Neurology
Peripheral Nervous System Neoplasms - diagnostic imaging
Positron-Emission Tomography - methods
Radiopharmaceuticals
Retroperitoneal Neoplasms - diagnostic imaging
Tomography
Tumors of the nervous system. Phacomatoses
title Peripheral nerve schwannoma: two cases exhibiting increased FDG uptake in early and delayed PET imaging
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