Base excision repair in nucleosomes lacking histone tails

Recently, we developed an in vitro system using human uracil DNA glycosylase (UDG), AP endonuclease (APE), DNA polymerase β (pol β) and rotationally positioned DNA containing a single uracil associated with a ‘designed’ nucleosome, to test short-patch base excision repair (BER) in chromatin. We foun...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	DNA repair 2005-02, Vol.4 (2), p.203-209
Hauptverfasser:	Beard, Brian C., Stevenson, Jill J., Wilson, Samuel H., Smerdon, Michael J.
Format:	Artikel
Sprache:	eng
Schlagworte:	AP endonuclease Bacteriology Biological and medical sciences Chromatin Chromatin. Chromosome DNA Glycosylases - metabolism DNA Helicases - metabolism DNA Polymerase beta - antagonists & inhibitors DNA Polymerase beta - metabolism DNA polymerase β DNA Repair DNA-(Apurinic or Apyrimidinic Site) Lyase - metabolism DNA-Binding Proteins - metabolism Exodeoxyribonucleases Fundamental and applied biological sciences. Psychology Glycosylase Growth, nutrition, cell differenciation Histones - genetics Histones - metabolism Humans Microbiology Molecular and cellular biology Molecular genetics Mutagenesis. Repair Nucleosomes - metabolism RecQ Helicases Tailless histones Uracil-DNA Glycosidase Werner Syndrome Helicase X-ray Repair Cross Complementing Protein 1
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!