The axon guidance defect of the telencephalic commissures of the JSAP1-deficient brain was partially rescued by the transgenic expression of JIP1
The JNK interacting protein, JSAP1, has been identified as a scaffold protein for mitogen-activated protein kinase (MAPK) signaling pathways and as a linker protein for the cargo transport along the axons. To investigate the physiological function of JSAP1 in vivo, we generated mice lacking JSAP1. T...
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Veröffentlicht in: | Developmental biology 2005, Vol.277 (1), p.184-199 |
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Hauptverfasser: | , , , , , , , , , , , |
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Sprache: | eng |
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