Combination Therapy with Rofecoxib and Finasteride in the Treatment of Men with Lower Urinary Tract Symptoms (LUTS) and Benign Prostatic Hyperplasia (BPH)

Cyclooxygenase-2 (COX-2) is expressed in human BPH tissue and displays either a pro-inflammatory effect or a proliferative effect on prostate cells. The aim of this study is to analyze whether combination therapy with rofecoxib, a COX-2 inhibitor, and finasteride offers an advantage compared to fina...

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Veröffentlicht in:	European urology 2005, Vol.47 (1), p.72-79
Hauptverfasser:	Di Silverio, Franco, Bosman, Cesare, Salvatori, Monti, Albanesi, Luca, Proietti Pannunzi, Laura, Ciccariello, Mauro, Cardi, Antonio, Salvatori, Gianfilippo, Sciarra, Alessandro
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Apoptosis Benign prostatic hyperplasia Cyclooxygenase Inhibitors - administration & dosage Drug Therapy, Combination Enzyme Inhibitors - administration & dosage Finasteride Finasteride - administration & dosage Humans Lactones - administration & dosage Male Middle Aged Prospective Studies Prostatic Hyperplasia - complications Prostatic Hyperplasia - drug therapy Rofecoxib Sulfones - administration & dosage Urologic Diseases - drug therapy Urologic Diseases - etiology
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