Usefulness of magnifying endoscopic evaluation of the terminal ileum for a patient with graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

The gastrointestinal tract is one of the common targets of acute graft-versus-host disease (GVHD), but accurate diagnosis is difficult because of the nonspecific nature of complicated diseases and the lack of diagnostic findings by conventional endoscopy. Recently, a magnifying endoscope has been de...

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Veröffentlicht in:Annals of hematology 2005-02, Vol.84 (2), p.106-109
Hauptverfasser: Onozawa, Masahiro, Yonezumi, Masakatsu, Kawarazaki, Mitsuru, Izumiyama, Koh, Chiba, Kouji, Kondo, Takeshi, Ota, Shuichi, Kobayashi, Sumiko, Kato, Mototsugu, Hashino, Satoshi, Tanaka, Junji, Imamura, Masahiro, Asaka, Masahiro
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container_end_page 109
container_issue 2
container_start_page 106
container_title Annals of hematology
container_volume 84
creator Onozawa, Masahiro
Yonezumi, Masakatsu
Kawarazaki, Mitsuru
Izumiyama, Koh
Chiba, Kouji
Kondo, Takeshi
Ota, Shuichi
Kobayashi, Sumiko
Kato, Mototsugu
Hashino, Satoshi
Tanaka, Junji
Imamura, Masahiro
Asaka, Masahiro
description The gastrointestinal tract is one of the common targets of acute graft-versus-host disease (GVHD), but accurate diagnosis is difficult because of the nonspecific nature of complicated diseases and the lack of diagnostic findings by conventional endoscopy. Recently, a magnifying endoscope has been developed and used for examining microstructures of the mucosa. Herein, we report the first use of a magnifying endoscope for a patient with gastrointestinal (GI) GVHD. Magnified endoscopic findings of atrophic and coalescent villi of the terminal ileum reflect histological findings of GVHD. Magnifying endoscopy of the terminal ileum may be useful for early detection and follow-up of GI GVHD.
doi_str_mv 10.1007/s00277-004-0915-2
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subjects Adolescent
Bone marrow
Endoscopy, Digestive System - methods
Graft vs Host Disease - pathology
Hematopoietic Stem Cell Transplantation - adverse effects
Humans
Ileal Diseases - pathology
Ileum - pathology
Intestinal Mucosa - pathology
Male
Stem cells
Transplantation, Homologous
Transplants & implants
title Usefulness of magnifying endoscopic evaluation of the terminal ileum for a patient with graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
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