Clinical Implications of Intermediate QRS Prolongation in the Absence of Bundle-Branch Block in Patients With ST-Segment-Elevation Acute Myocardial Infarction
Background In the reperfusion era the clinical characteristics of intermediate QRS prolongation without bundle-branch block (BBB) remain unclear in patients with ST-segment elevation myocardial infarction (STEMI). Methods and Results A total of 465 patients with STEMI within 24 h of onset were class...
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Veröffentlicht in: | Circulation Journal 2005, Vol.69(1), pp.29-34 |
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creator | Tsukahara, Kengo Kimura, Kazuo Kosuge, Masami Shimizu, Tomoaki Sugano, Teruyasu Hibi, Kiyoshi Kanna, Masahiko Toda, Noritaka Takamura, Takeshi Okuda, Jun Nozawa, Naoki Furukawa, Eri Umemura, Satoshi |
description | Background In the reperfusion era the clinical characteristics of intermediate QRS prolongation without bundle-branch block (BBB) remain unclear in patients with ST-segment elevation myocardial infarction (STEMI). Methods and Results A total of 465 patients with STEMI within 24 h of onset were classified into 3 groups according to QRS duration on presenting electrocardiograms: 338 patients had QRS duration 1 was higher in group W (28%) than in group N (12%), but lower than in group B (47%) (p |
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Methods and Results A total of 465 patients with STEMI within 24 h of onset were classified into 3 groups according to QRS duration on presenting electrocardiograms: 338 patients had QRS duration <100 ms (group N), 71 had QRS duration ≥100 ms without BBB (group W), and 56 had BBB (group B). The frequency of Killip class >1 was higher in group W (28%) than in group N (12%), but lower than in group B (47%) (p<0.05, respectively). The percentages of patients with non-anterior infarction (69% vs 42%, 47%), 3-vessel disease (30% vs 9%, 16%), and coronary artery bypass graft surgery (24% vs 4%, 13%) were higher in group W than in groups N and B (all p<0.05). In group W, 6-month-mortality was similar to that in group N, but lower than that in group B (4%, 3% vs 25%, p<0.05 respectively). Conclusions In the reperfusion era, although patients with intermediate QRS prolongation without BBB have more severe coronary disease, 6-month-mortality is similar to those with normal conduction, but lower than those with BBB. (Circ J 2005; 69: 29 - 34)</description><identifier>ISSN: 1346-9843</identifier><identifier>EISSN: 1347-4820</identifier><identifier>DOI: 10.1253/circj.69.29</identifier><identifier>PMID: 15635198</identifier><language>eng</language><publisher>Japan: The Japanese Circulation Society</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Arrhythmias, Cardiac - physiopathology ; Bundle-Branch Block ; Chest Pain - physiopathology ; Coronary Angiography ; Coronary Circulation - physiology ; Electrocardiography ; Female ; Heart Failure - epidemiology ; Humans ; Hypotension - epidemiology ; Male ; Middle Aged ; Myocardial infarction ; Myocardial Infarction - mortality ; Myocardial Infarction - physiopathology ; Myocardial Infarction - therapy ; Reperfusion ; Retrospective Studies ; Survival Analysis</subject><ispartof>Circulation Journal, 2005, Vol.69(1), pp.29-34</ispartof><rights>2005 THE JAPANESE CIRCULATION SOCIETY</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c447t-4c4682880b16b8257be47cfa358c96754f1238b3b5d44e91c8dcc624c780b4b03</citedby><cites>FETCH-LOGICAL-c447t-4c4682880b16b8257be47cfa358c96754f1238b3b5d44e91c8dcc624c780b4b03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1876,4009,27902,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15635198$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tsukahara, Kengo</creatorcontrib><creatorcontrib>Kimura, Kazuo</creatorcontrib><creatorcontrib>Kosuge, Masami</creatorcontrib><creatorcontrib>Shimizu, Tomoaki</creatorcontrib><creatorcontrib>Sugano, Teruyasu</creatorcontrib><creatorcontrib>Hibi, Kiyoshi</creatorcontrib><creatorcontrib>Kanna, Masahiko</creatorcontrib><creatorcontrib>Toda, Noritaka</creatorcontrib><creatorcontrib>Takamura, Takeshi</creatorcontrib><creatorcontrib>Okuda, Jun</creatorcontrib><creatorcontrib>Nozawa, Naoki</creatorcontrib><creatorcontrib>Furukawa, Eri</creatorcontrib><creatorcontrib>Umemura, Satoshi</creatorcontrib><title>Clinical Implications of Intermediate QRS Prolongation in the Absence of Bundle-Branch Block in Patients With ST-Segment-Elevation Acute Myocardial Infarction</title><title>Circulation Journal</title><addtitle>Circ J</addtitle><description>Background In the reperfusion era the clinical characteristics of intermediate QRS prolongation without bundle-branch block (BBB) remain unclear in patients with ST-segment elevation myocardial infarction (STEMI). Methods and Results A total of 465 patients with STEMI within 24 h of onset were classified into 3 groups according to QRS duration on presenting electrocardiograms: 338 patients had QRS duration <100 ms (group N), 71 had QRS duration ≥100 ms without BBB (group W), and 56 had BBB (group B). The frequency of Killip class >1 was higher in group W (28%) than in group N (12%), but lower than in group B (47%) (p<0.05, respectively). The percentages of patients with non-anterior infarction (69% vs 42%, 47%), 3-vessel disease (30% vs 9%, 16%), and coronary artery bypass graft surgery (24% vs 4%, 13%) were higher in group W than in groups N and B (all p<0.05). In group W, 6-month-mortality was similar to that in group N, but lower than that in group B (4%, 3% vs 25%, p<0.05 respectively). Conclusions In the reperfusion era, although patients with intermediate QRS prolongation without BBB have more severe coronary disease, 6-month-mortality is similar to those with normal conduction, but lower than those with BBB. (Circ J 2005; 69: 29 - 34)</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Arrhythmias, Cardiac - physiopathology</subject><subject>Bundle-Branch Block</subject><subject>Chest Pain - physiopathology</subject><subject>Coronary Angiography</subject><subject>Coronary Circulation - physiology</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Heart Failure - epidemiology</subject><subject>Humans</subject><subject>Hypotension - epidemiology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myocardial infarction</subject><subject>Myocardial Infarction - mortality</subject><subject>Myocardial Infarction - physiopathology</subject><subject>Myocardial Infarction - therapy</subject><subject>Reperfusion</subject><subject>Retrospective Studies</subject><subject>Survival Analysis</subject><issn>1346-9843</issn><issn>1347-4820</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkU2PEzEMhkcIxC4LJ-4oJy5oSr4mk9xoqwUqLWKhiziOMm6mTclkSpJB2j_DbyXtVPRiW_bj15ZdFK8JnhFasfdgA-xnQs2oelJcE8brkkuKn55iUSrJ2VXxIsY9xlThSj0vrkglWEWUvC7-Lp31FrRDq_7gcpDs4CMaOrTyyYTebKxOBn37vkb3YXCD354IZD1KO4PmbTQezJFfjH7jTLkI2sMOLdwAv47UfeaNTxH9tGmH1g_l2mz7nChvnfkzac1hzCO-PA6gQx6XV_GdDnCsvSyeddpF8-rsb4ofH28flp_Lu6-fVsv5XQmc16nkwIWkUuKWiFbSqm4Nr6HTrJKgRF3xjlAmW9ZWG86NIiA3AIJyqHMLbzG7Kd5Ouocw_B5NTE1vIxjntDfDGBtRM44rLDL4bgIhDDEG0zWHYHsdHhuCm-M7mtM7GqEaqjL95iw7tvmUF_Z8_wx8mIB9THpr_gM6JAvOXMTIZKi6lHY6NMazf6cmn-U</recordid><startdate>2005</startdate><enddate>2005</enddate><creator>Tsukahara, Kengo</creator><creator>Kimura, Kazuo</creator><creator>Kosuge, Masami</creator><creator>Shimizu, Tomoaki</creator><creator>Sugano, Teruyasu</creator><creator>Hibi, Kiyoshi</creator><creator>Kanna, Masahiko</creator><creator>Toda, Noritaka</creator><creator>Takamura, Takeshi</creator><creator>Okuda, Jun</creator><creator>Nozawa, Naoki</creator><creator>Furukawa, Eri</creator><creator>Umemura, Satoshi</creator><general>The Japanese Circulation Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2005</creationdate><title>Clinical Implications of Intermediate QRS Prolongation in the Absence of Bundle-Branch Block in Patients With ST-Segment-Elevation Acute Myocardial Infarction</title><author>Tsukahara, Kengo ; Kimura, Kazuo ; Kosuge, Masami ; Shimizu, Tomoaki ; Sugano, Teruyasu ; Hibi, Kiyoshi ; Kanna, Masahiko ; Toda, Noritaka ; Takamura, Takeshi ; Okuda, Jun ; Nozawa, Naoki ; Furukawa, Eri ; Umemura, Satoshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c447t-4c4682880b16b8257be47cfa358c96754f1238b3b5d44e91c8dcc624c780b4b03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Arrhythmias, Cardiac - physiopathology</topic><topic>Bundle-Branch Block</topic><topic>Chest Pain - physiopathology</topic><topic>Coronary Angiography</topic><topic>Coronary Circulation - physiology</topic><topic>Electrocardiography</topic><topic>Female</topic><topic>Heart Failure - epidemiology</topic><topic>Humans</topic><topic>Hypotension - epidemiology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Myocardial infarction</topic><topic>Myocardial Infarction - mortality</topic><topic>Myocardial Infarction - physiopathology</topic><topic>Myocardial Infarction - therapy</topic><topic>Reperfusion</topic><topic>Retrospective Studies</topic><topic>Survival Analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tsukahara, Kengo</creatorcontrib><creatorcontrib>Kimura, Kazuo</creatorcontrib><creatorcontrib>Kosuge, Masami</creatorcontrib><creatorcontrib>Shimizu, Tomoaki</creatorcontrib><creatorcontrib>Sugano, Teruyasu</creatorcontrib><creatorcontrib>Hibi, Kiyoshi</creatorcontrib><creatorcontrib>Kanna, Masahiko</creatorcontrib><creatorcontrib>Toda, Noritaka</creatorcontrib><creatorcontrib>Takamura, Takeshi</creatorcontrib><creatorcontrib>Okuda, Jun</creatorcontrib><creatorcontrib>Nozawa, Naoki</creatorcontrib><creatorcontrib>Furukawa, Eri</creatorcontrib><creatorcontrib>Umemura, Satoshi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Circulation Journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tsukahara, Kengo</au><au>Kimura, Kazuo</au><au>Kosuge, Masami</au><au>Shimizu, Tomoaki</au><au>Sugano, Teruyasu</au><au>Hibi, Kiyoshi</au><au>Kanna, Masahiko</au><au>Toda, Noritaka</au><au>Takamura, Takeshi</au><au>Okuda, Jun</au><au>Nozawa, Naoki</au><au>Furukawa, Eri</au><au>Umemura, Satoshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical Implications of Intermediate QRS Prolongation in the Absence of Bundle-Branch Block in Patients With ST-Segment-Elevation Acute Myocardial Infarction</atitle><jtitle>Circulation Journal</jtitle><addtitle>Circ J</addtitle><date>2005</date><risdate>2005</risdate><volume>69</volume><issue>1</issue><spage>29</spage><epage>34</epage><pages>29-34</pages><issn>1346-9843</issn><eissn>1347-4820</eissn><abstract>Background In the reperfusion era the clinical characteristics of intermediate QRS prolongation without bundle-branch block (BBB) remain unclear in patients with ST-segment elevation myocardial infarction (STEMI). Methods and Results A total of 465 patients with STEMI within 24 h of onset were classified into 3 groups according to QRS duration on presenting electrocardiograms: 338 patients had QRS duration <100 ms (group N), 71 had QRS duration ≥100 ms without BBB (group W), and 56 had BBB (group B). The frequency of Killip class >1 was higher in group W (28%) than in group N (12%), but lower than in group B (47%) (p<0.05, respectively). The percentages of patients with non-anterior infarction (69% vs 42%, 47%), 3-vessel disease (30% vs 9%, 16%), and coronary artery bypass graft surgery (24% vs 4%, 13%) were higher in group W than in groups N and B (all p<0.05). In group W, 6-month-mortality was similar to that in group N, but lower than that in group B (4%, 3% vs 25%, p<0.05 respectively). Conclusions In the reperfusion era, although patients with intermediate QRS prolongation without BBB have more severe coronary disease, 6-month-mortality is similar to those with normal conduction, but lower than those with BBB. (Circ J 2005; 69: 29 - 34)</abstract><cop>Japan</cop><pub>The Japanese Circulation Society</pub><pmid>15635198</pmid><doi>10.1253/circj.69.29</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged Aged, 80 and over Arrhythmias, Cardiac - physiopathology Bundle-Branch Block Chest Pain - physiopathology Coronary Angiography Coronary Circulation - physiology Electrocardiography Female Heart Failure - epidemiology Humans Hypotension - epidemiology Male Middle Aged Myocardial infarction Myocardial Infarction - mortality Myocardial Infarction - physiopathology Myocardial Infarction - therapy Reperfusion Retrospective Studies Survival Analysis |
title | Clinical Implications of Intermediate QRS Prolongation in the Absence of Bundle-Branch Block in Patients With ST-Segment-Elevation Acute Myocardial Infarction |
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