Transepithelial pressure pulses induce nucleotide release in polarized MDCK cells

The release of nucleotides is involved in mechanosensation in various epithelial cells. Intriguingly, kidney epithelial cells are absolutely dependent on the primary cilium to sense changes in apical laminar flow. During fluid passage, the renal epithelial cells are subjected to various mechanical s...

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Veröffentlicht in:	American journal of physiology. Renal physiology 2005-01, Vol.288 (1), p.F133-F141
Hauptverfasser:	Praetorius, H A, Frøkiaer, J, Leipziger, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Animals Calcium - metabolism Cell Line Cilia - physiology Dogs Epithelial Cells - metabolism Kidney - cytology Kidney - metabolism Mechanotransduction, Cellular - physiology Pressure
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