The Effects of Acute Isovolemic Hemodilution on Oxygenation During One-Lung Ventilation
Data on the effects of isovolemic hemodilution (IH) on oxygenation during one-lung ventilation (OLV) are lacking. We studied 47 patients with hemoglobin >14 g/dL who were scheduled for lung surgery (17 with normal lung function [group NL], 17 with chronic obstructive pulmonary disease [COPD] [gro...
Gespeichert in:
| Veröffentlicht in: | Anesthesia and analgesia 2005-01, Vol.100 (1), p.15-20 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 20 |
|---|---|
| container_issue | 1 |
| container_start_page | 15 |
| container_title | Anesthesia and analgesia |
| container_volume | 100 |
| creator | Szegedi, Laszlo L. Linden, Philippe Van der Ducart, Anne Cosaert, Pieter Poelaert, Jan Vermassen, Frank Mortier, Eric P. d’Hollander, Alain A. |
| description | Data on the effects of isovolemic hemodilution (IH) on oxygenation during one-lung ventilation (OLV) are lacking. We studied 47 patients with hemoglobin >14 g/dL who were scheduled for lung surgery (17 with normal lung function [group NL], 17 with chronic obstructive pulmonary disease [COPD] [group COPD], and 13 with COPD as control for time/anesthesia effects [group CTRL]). Anesthesia was standardized. The tracheas were intubated with a double-lumen tube. Ventilatory settings and fraction of inspired oxygen remained constant. The study was performed with patients in the supine position before surgery. OLV was initiated for 15 min. Two-lung ventilation was reinstituted, and IH was performed (500 mL); an identical volume of hydroxyethyl starch was administered. Subsequently, OLV was again performed for 15 min. In group CTRL, the same sequences of OLV were performed without IH. At the end of each period of OLV, pulmonary mechanics and blood gases were recorded. Data were analyzed by analysis of variance (mean ± sd). In group NL and group CTRL, the arterial oxygen partial pressure remained constant, whereas it decreased in group COPD from 119 ± 21 mm Hg before IH to 86 ± 16 mm Hg after IH (P < 0.01). Mild IH impairs gas exchange during OLV in COPD patients, but not in patients with normal lung function. |
| doi_str_mv | 10.1213/01.ANE.0000136771.64552.9C |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67338944</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>67338944</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4444-ba9e0938ed385ccb99b59f682206d6082fddfe3afecc4bca3d26b4cd150b70d43</originalsourceid><addsrcrecordid>eNpFkdtu1DAQhi0EotuFV0AREtwl-JyYu9WypZVW7E2BS8txxt2AExc7ofTt8R6kHVmaGfubGesfhN4TXBFK2CdMqtW3TYWzESbrmlSSC0ErtX6BFkRQWdZCNS_RIgOspEqpK3Sd0q8Djxv5Gl0RIYnEXCzQz_s9FBvnwE6pCK5Y2XmC4i6Fv8HD0NviFobQ9X6e-jAW-ez-PT_AaI7plzn240OxG6Hczjn4AePU--PbG_TKGZ_g7dkv0febzf36ttzuvt6tV9vS8mxlaxRgxRroWCOsbZVqhXKyoRTLTuKGuq5zwEz-n-WtNayjsuW2IwK3Ne44W6KPp76PMfyZIU166JMF780IYU5a1ow1ih_AzyfQxpBSBKcfYz-Y-KwJ1gdZNSY6y6ovsuqjrFqtc_G785S5HaC7lJ51zMCHM2CSNd5FM9o-XTjJJeV5G0vET9xT8BPE9NvPTxD1Hoyf9sfRWDBV0uzyrjAuDzec_QftdpEI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>67338944</pqid></control><display><type>article</type><title>The Effects of Acute Isovolemic Hemodilution on Oxygenation During One-Lung Ventilation</title><source>MEDLINE</source><source>Journals@Ovid LWW Legacy Archive</source><source>Journals@Ovid Complete</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Szegedi, Laszlo L. ; Linden, Philippe Van der ; Ducart, Anne ; Cosaert, Pieter ; Poelaert, Jan ; Vermassen, Frank ; Mortier, Eric P. ; d’Hollander, Alain A.</creator><creatorcontrib>Szegedi, Laszlo L. ; Linden, Philippe Van der ; Ducart, Anne ; Cosaert, Pieter ; Poelaert, Jan ; Vermassen, Frank ; Mortier, Eric P. ; d’Hollander, Alain A.</creatorcontrib><description>Data on the effects of isovolemic hemodilution (IH) on oxygenation during one-lung ventilation (OLV) are lacking. We studied 47 patients with hemoglobin >14 g/dL who were scheduled for lung surgery (17 with normal lung function [group NL], 17 with chronic obstructive pulmonary disease [COPD] [group COPD], and 13 with COPD as control for time/anesthesia effects [group CTRL]). Anesthesia was standardized. The tracheas were intubated with a double-lumen tube. Ventilatory settings and fraction of inspired oxygen remained constant. The study was performed with patients in the supine position before surgery. OLV was initiated for 15 min. Two-lung ventilation was reinstituted, and IH was performed (500 mL); an identical volume of hydroxyethyl starch was administered. Subsequently, OLV was again performed for 15 min. In group CTRL, the same sequences of OLV were performed without IH. At the end of each period of OLV, pulmonary mechanics and blood gases were recorded. Data were analyzed by analysis of variance (mean ± sd). In group NL and group CTRL, the arterial oxygen partial pressure remained constant, whereas it decreased in group COPD from 119 ± 21 mm Hg before IH to 86 ± 16 mm Hg after IH (P < 0.01). Mild IH impairs gas exchange during OLV in COPD patients, but not in patients with normal lung function.</description><identifier>ISSN: 0003-2999</identifier><identifier>EISSN: 1526-7598</identifier><identifier>DOI: 10.1213/01.ANE.0000136771.64552.9C</identifier><identifier>PMID: 15616045</identifier><identifier>CODEN: AACRAT</identifier><language>eng</language><publisher>Hagerstown, MD: International Anesthesia Research Society</publisher><subject>Aged ; Anesthesia ; Anesthesia, General ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Blood Gas Analysis ; Echocardiography, Transesophageal ; Female ; Hematocrit ; Hemodilution ; Hemodynamics ; Hemoglobins - metabolism ; Humans ; Intraoperative Period ; Male ; Medical sciences ; Middle Aged ; Monitoring, Intraoperative ; Oxygen - blood ; Positive-Pressure Respiration ; Pulmonary Disease, Chronic Obstructive - complications ; Pulmonary Disease, Chronic Obstructive - physiopathology ; Respiration, Artificial ; Respiratory Function Tests ; Supine Position - physiology ; Thoracic Surgical Procedures</subject><ispartof>Anesthesia and analgesia, 2005-01, Vol.100 (1), p.15-20</ispartof><rights>International Anesthesia Research Society</rights><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4444-ba9e0938ed385ccb99b59f682206d6082fddfe3afecc4bca3d26b4cd150b70d43</citedby><cites>FETCH-LOGICAL-c4444-ba9e0938ed385ccb99b59f682206d6082fddfe3afecc4bca3d26b4cd150b70d43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&NEWS=n&CSC=Y&PAGE=fulltext&D=ovft&AN=00000539-200501000-00004$$EHTML$$P50$$Gwolterskluwer$$H</linktohtml><link.rule.ids>314,780,784,4022,4607,27922,27923,27924,65232</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16462400$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15616045$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Szegedi, Laszlo L.</creatorcontrib><creatorcontrib>Linden, Philippe Van der</creatorcontrib><creatorcontrib>Ducart, Anne</creatorcontrib><creatorcontrib>Cosaert, Pieter</creatorcontrib><creatorcontrib>Poelaert, Jan</creatorcontrib><creatorcontrib>Vermassen, Frank</creatorcontrib><creatorcontrib>Mortier, Eric P.</creatorcontrib><creatorcontrib>d’Hollander, Alain A.</creatorcontrib><title>The Effects of Acute Isovolemic Hemodilution on Oxygenation During One-Lung Ventilation</title><title>Anesthesia and analgesia</title><addtitle>Anesth Analg</addtitle><description>Data on the effects of isovolemic hemodilution (IH) on oxygenation during one-lung ventilation (OLV) are lacking. We studied 47 patients with hemoglobin >14 g/dL who were scheduled for lung surgery (17 with normal lung function [group NL], 17 with chronic obstructive pulmonary disease [COPD] [group COPD], and 13 with COPD as control for time/anesthesia effects [group CTRL]). Anesthesia was standardized. The tracheas were intubated with a double-lumen tube. Ventilatory settings and fraction of inspired oxygen remained constant. The study was performed with patients in the supine position before surgery. OLV was initiated for 15 min. Two-lung ventilation was reinstituted, and IH was performed (500 mL); an identical volume of hydroxyethyl starch was administered. Subsequently, OLV was again performed for 15 min. In group CTRL, the same sequences of OLV were performed without IH. At the end of each period of OLV, pulmonary mechanics and blood gases were recorded. Data were analyzed by analysis of variance (mean ± sd). In group NL and group CTRL, the arterial oxygen partial pressure remained constant, whereas it decreased in group COPD from 119 ± 21 mm Hg before IH to 86 ± 16 mm Hg after IH (P < 0.01). Mild IH impairs gas exchange during OLV in COPD patients, but not in patients with normal lung function.</description><subject>Aged</subject><subject>Anesthesia</subject><subject>Anesthesia, General</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Blood Gas Analysis</subject><subject>Echocardiography, Transesophageal</subject><subject>Female</subject><subject>Hematocrit</subject><subject>Hemodilution</subject><subject>Hemodynamics</subject><subject>Hemoglobins - metabolism</subject><subject>Humans</subject><subject>Intraoperative Period</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Monitoring, Intraoperative</subject><subject>Oxygen - blood</subject><subject>Positive-Pressure Respiration</subject><subject>Pulmonary Disease, Chronic Obstructive - complications</subject><subject>Pulmonary Disease, Chronic Obstructive - physiopathology</subject><subject>Respiration, Artificial</subject><subject>Respiratory Function Tests</subject><subject>Supine Position - physiology</subject><subject>Thoracic Surgical Procedures</subject><issn>0003-2999</issn><issn>1526-7598</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkdtu1DAQhi0EotuFV0AREtwl-JyYu9WypZVW7E2BS8txxt2AExc7ofTt8R6kHVmaGfubGesfhN4TXBFK2CdMqtW3TYWzESbrmlSSC0ErtX6BFkRQWdZCNS_RIgOspEqpK3Sd0q8Djxv5Gl0RIYnEXCzQz_s9FBvnwE6pCK5Y2XmC4i6Fv8HD0NviFobQ9X6e-jAW-ez-PT_AaI7plzn240OxG6Hczjn4AePU--PbG_TKGZ_g7dkv0febzf36ttzuvt6tV9vS8mxlaxRgxRroWCOsbZVqhXKyoRTLTuKGuq5zwEz-n-WtNayjsuW2IwK3Ne44W6KPp76PMfyZIU166JMF780IYU5a1ow1ih_AzyfQxpBSBKcfYz-Y-KwJ1gdZNSY6y6ovsuqjrFqtc_G785S5HaC7lJ51zMCHM2CSNd5FM9o-XTjJJeV5G0vET9xT8BPE9NvPTxD1Hoyf9sfRWDBV0uzyrjAuDzec_QftdpEI</recordid><startdate>20050101</startdate><enddate>20050101</enddate><creator>Szegedi, Laszlo L.</creator><creator>Linden, Philippe Van der</creator><creator>Ducart, Anne</creator><creator>Cosaert, Pieter</creator><creator>Poelaert, Jan</creator><creator>Vermassen, Frank</creator><creator>Mortier, Eric P.</creator><creator>d’Hollander, Alain A.</creator><general>International Anesthesia Research Society</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20050101</creationdate><title>The Effects of Acute Isovolemic Hemodilution on Oxygenation During One-Lung Ventilation</title><author>Szegedi, Laszlo L. ; Linden, Philippe Van der ; Ducart, Anne ; Cosaert, Pieter ; Poelaert, Jan ; Vermassen, Frank ; Mortier, Eric P. ; d’Hollander, Alain A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4444-ba9e0938ed385ccb99b59f682206d6082fddfe3afecc4bca3d26b4cd150b70d43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Aged</topic><topic>Anesthesia</topic><topic>Anesthesia, General</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Blood Gas Analysis</topic><topic>Echocardiography, Transesophageal</topic><topic>Female</topic><topic>Hematocrit</topic><topic>Hemodilution</topic><topic>Hemodynamics</topic><topic>Hemoglobins - metabolism</topic><topic>Humans</topic><topic>Intraoperative Period</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Monitoring, Intraoperative</topic><topic>Oxygen - blood</topic><topic>Positive-Pressure Respiration</topic><topic>Pulmonary Disease, Chronic Obstructive - complications</topic><topic>Pulmonary Disease, Chronic Obstructive - physiopathology</topic><topic>Respiration, Artificial</topic><topic>Respiratory Function Tests</topic><topic>Supine Position - physiology</topic><topic>Thoracic Surgical Procedures</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Szegedi, Laszlo L.</creatorcontrib><creatorcontrib>Linden, Philippe Van der</creatorcontrib><creatorcontrib>Ducart, Anne</creatorcontrib><creatorcontrib>Cosaert, Pieter</creatorcontrib><creatorcontrib>Poelaert, Jan</creatorcontrib><creatorcontrib>Vermassen, Frank</creatorcontrib><creatorcontrib>Mortier, Eric P.</creatorcontrib><creatorcontrib>d’Hollander, Alain A.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Anesthesia and analgesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Szegedi, Laszlo L.</au><au>Linden, Philippe Van der</au><au>Ducart, Anne</au><au>Cosaert, Pieter</au><au>Poelaert, Jan</au><au>Vermassen, Frank</au><au>Mortier, Eric P.</au><au>d’Hollander, Alain A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Effects of Acute Isovolemic Hemodilution on Oxygenation During One-Lung Ventilation</atitle><jtitle>Anesthesia and analgesia</jtitle><addtitle>Anesth Analg</addtitle><date>2005-01-01</date><risdate>2005</risdate><volume>100</volume><issue>1</issue><spage>15</spage><epage>20</epage><pages>15-20</pages><issn>0003-2999</issn><eissn>1526-7598</eissn><coden>AACRAT</coden><abstract>Data on the effects of isovolemic hemodilution (IH) on oxygenation during one-lung ventilation (OLV) are lacking. We studied 47 patients with hemoglobin >14 g/dL who were scheduled for lung surgery (17 with normal lung function [group NL], 17 with chronic obstructive pulmonary disease [COPD] [group COPD], and 13 with COPD as control for time/anesthesia effects [group CTRL]). Anesthesia was standardized. The tracheas were intubated with a double-lumen tube. Ventilatory settings and fraction of inspired oxygen remained constant. The study was performed with patients in the supine position before surgery. OLV was initiated for 15 min. Two-lung ventilation was reinstituted, and IH was performed (500 mL); an identical volume of hydroxyethyl starch was administered. Subsequently, OLV was again performed for 15 min. In group CTRL, the same sequences of OLV were performed without IH. At the end of each period of OLV, pulmonary mechanics and blood gases were recorded. Data were analyzed by analysis of variance (mean ± sd). In group NL and group CTRL, the arterial oxygen partial pressure remained constant, whereas it decreased in group COPD from 119 ± 21 mm Hg before IH to 86 ± 16 mm Hg after IH (P < 0.01). Mild IH impairs gas exchange during OLV in COPD patients, but not in patients with normal lung function.</abstract><cop>Hagerstown, MD</cop><pub>International Anesthesia Research Society</pub><pmid>15616045</pmid><doi>10.1213/01.ANE.0000136771.64552.9C</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-2999 |
| ispartof | Anesthesia and analgesia, 2005-01, Vol.100 (1), p.15-20 |
| issn | 0003-2999 1526-7598 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67338944 |
| source | MEDLINE; Journals@Ovid LWW Legacy Archive; Journals@Ovid Complete; EZB-FREE-00999 freely available EZB journals |
| subjects | Aged Anesthesia Anesthesia, General Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Gas Analysis Echocardiography, Transesophageal Female Hematocrit Hemodilution Hemodynamics Hemoglobins - metabolism Humans Intraoperative Period Male Medical sciences Middle Aged Monitoring, Intraoperative Oxygen - blood Positive-Pressure Respiration Pulmonary Disease, Chronic Obstructive - complications Pulmonary Disease, Chronic Obstructive - physiopathology Respiration, Artificial Respiratory Function Tests Supine Position - physiology Thoracic Surgical Procedures |
| title | The Effects of Acute Isovolemic Hemodilution on Oxygenation During One-Lung Ventilation |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T00%3A38%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20Effects%20of%20Acute%20Isovolemic%20Hemodilution%20on%20Oxygenation%20During%20One-Lung%20Ventilation&rft.jtitle=Anesthesia%20and%20analgesia&rft.au=Szegedi,%20Laszlo%20L.&rft.date=2005-01-01&rft.volume=100&rft.issue=1&rft.spage=15&rft.epage=20&rft.pages=15-20&rft.issn=0003-2999&rft.eissn=1526-7598&rft.coden=AACRAT&rft_id=info:doi/10.1213/01.ANE.0000136771.64552.9C&rft_dat=%3Cproquest_cross%3E67338944%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=67338944&rft_id=info:pmid/15616045&rfr_iscdi=true |