The expression of RANTES and chemokine receptors in the brains of scrapie-infected mice

While chemokines play an important role in host defense, it has become abundantly clear that their expression is not solely restricted to immune cells. In this study, to investigate the role of chemokines in pathogenic mechanism of neurodegeneration in prion diseases, we determined the cerebral expr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neuroimmunology 2005, Vol.158 (1), p.26-33
Hauptverfasser:	Lee, Hyun-Pil, Jun, Yong-Cheol, Choi, Jin-Kyu, Kim, Jae-Il, I. Carp, Richard, Kim, Yong-Sun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocyte Blotting, Southern - methods Blotting, Western - methods Brain - anatomy & histology Brain - metabolism Chemokine Chemokine CCL5 - genetics Chemokine CCL5 - metabolism Electrophoretic Mobility Shift Assay - methods Gene Expression Regulation Glial Fibrillary Acidic Protein - metabolism Immunohistochemistry - methods Immunoprecipitation - methods Male Mice Mice, Inbred C57BL Microglia Prion disease RANTES Receptors, Chemokine - genetics Receptors, Chemokine - metabolism Reverse Transcriptase Polymerase Chain Reaction - methods RNA, Messenger - metabolism Scrapie - genetics Scrapie - metabolism Transmissible spongiform encephalopathy
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!