Uremia accelerates both atherosclerosis and arterial calcification in apolipoprotein E knockout mice

Chronic renal failure (CRF) favors the development of atherosclerosis and excessive calcification of atheromatous lesions. CRF was induced in apolipoprotein E knockout (apoE(-/-)) mice to study (1) a possible acceleration of aortic atherosclerosis, (2) the degree and type of vascular calcification,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of the American Society of Nephrology 2005, Vol.16 (1), p.109-116
Hauptverfasser:	MASSY, Ziad A, IVANOVSKI, Ognen, MUNTZEL, Martin S, NGUYEN-KHOA, Thao, ANGULO, Jesus, SZUMILAK, Dorota, MOTHU, Nadya, PHAN, Olivier, DAUDON, Michel, LACOUR, Bernard, DRÜEKE, Tilman B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - metabolism Aorta - pathology Apolipoproteins E - genetics Arteriosclerosis - pathology Arteriosclerosis - physiopathology Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Body Weight Calcinosis - pathology Calcinosis - physiopathology Cardiology. Vascular system Cholesterol - blood Collagen - metabolism Disease Models, Animal Disease Progression Female Kidney Failure, Chronic - pathology Kidney Failure, Chronic - physiopathology Macrophages - pathology Male Medical sciences Mice Mice, Inbred C57BL Mice, Knockout Monocytes - pathology Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Renal failure Triglycerides - blood Urea - blood Uremia - pathology Uremia - physiopathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!