Peptide immunogens designed to enhance immune responses against human immunodeficiency virus (HIV) mutant strains: a plausible means of preventing viral persistence

A major problem impeding the development of an effective HIV-1 vaccine is the rapid antigenic variability that occurs throughout the viral genome but is most pronounced in the envelope ( env) gene and env gene products. The high number of errors made by the reverse transcriptase (RT) enzyme and the...

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Veröffentlicht in:Journal of theoretical biology 2005-03, Vol.233 (1), p.85-90
Hauptverfasser: Hewer, R., Meyer, D.
Format: Artikel
Sprache:eng
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