Enhanced egg-induced immunopathology correlates with high IFN-gamma in murine schistosomiasis: identification of two epistatic genetic intervals

The genetic basis of dissimilar immunopathology development among mouse strains infected with Schistosoma mansoni is not known. We performed a multipoint parametric linkage analysis on a cohort of F(2) mice, offspring of brother-sister mating between (high pathology CBA x low pathology BL/6)F(1) mic...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of immunology (1950) 2005-01, Vol.174 (1), p.435-440
Hauptverfasser:	Rutitzky, Laura I, Hernandez, Hector J, Yim, Young-Sun, Ricklan, David E, Finger, Eduardo, Mohan, Chandra, Peter, Inga, Wakeland, Edward K, Stadecker, Miguel J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromosome Mapping Disease Models, Animal Epistasis, Genetic Female Genetic Linkage Granuloma - pathology Interferon-gamma - biosynthesis Interferon-gamma - immunology Liver Diseases, Parasitic - pathology Male Mice Ovum - immunology Polymerase Chain Reaction Schistosoma mansoni Schistosomiasis - genetics Species Specificity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!