Effects of Depletion of CREB-binding Protein on c-Myc Regulation and Cell Cycle G1-S Transition

We recently reported that the transcriptional coactivator and histone acetyltransferase p300 plays an important role in the G1 phase of the cell cycle by negatively regulating c-myc and thereby preventing premature G1 exit (Kolli, et al. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 4646–4651; Balucham...

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Veröffentlicht in:	The Journal of biological chemistry 2005-01, Vol.280 (1), p.361-374
Hauptverfasser:	Rajabi, Hasan N., Baluchamy, Sudhakar, Kolli, Sivanagarani, Nag, Alo, Srinivas, Rampalli, Raychaudhuri, Pradip, Thimmapaya, Bayar
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Cycle - genetics Cell Line CREB-Binding Protein G1 Phase - genetics Gene Expression Regulation Genes, myc Humans Nuclear Proteins - antagonists & inhibitors Nuclear Proteins - genetics Proto-Oncogene Proteins c-myc - genetics S Phase - genetics Trans-Activators - antagonists & inhibitors Trans-Activators - genetics
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