The novel pyrimidine and purine derivatives of l-ascorbic acid: synthesis, one- and two-dimensional 1H and 13C NMR study, cytostatic and antiviral evaluation

Novel C-5 substituted pyrimidine ( 6– 15) and purine ( 18– 20) derivatives of l-ascorbic acid containing free hydroxy groups at C-2′ or C-2′ and C-3′ positions of the lactone ring were synthesized and evaluated for their cytostatic and antiviral activities. The syntheses of the novel C-5 substituted...

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Veröffentlicht in:Bioorganic & medicinal chemistry 2005-01, Vol.13 (1), p.131-139
Hauptverfasser: Gazivoda, Tatjana, Plevnik, Miha, Plavec, Janez, Kraljević, Sandra, Kralj, Marijeta, Pavelić, Krešimir, Balzarini, Jan, Clercq, Erik De, Mintas, Mladen, Raić-Malić, Silvana
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Sprache:eng
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