Alternative Runx1 promoter usage in mouse developmental hematopoiesis

The interest in stem cell based therapies has emphasized the importance of understanding the cellular and molecular mechanisms by which stem cells are generated in ontogeny and maintained throughout adult life. Hematopoietic stem cells (HSCs) are first found in clusters of hematopoietic cells buddin...

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Veröffentlicht in:	Blood cells, molecules, & diseases molecules, & diseases, 2009-07, Vol.43 (1), p.35-42
Hauptverfasser:	Bee, Thomas, Liddiard, Kate, Swiers, Gemma, Bickley, Sorrel R.B., Vink, Chris S., Jarratt, Andrew, Hughes, Jim R., Medvinsky, Alexander, de Bruijn, Marella F.T.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - cytology Aorta - embryology Aorta - physiology Base Sequence Core Binding Factor Alpha 2 Subunit - genetics Core Binding Factor Alpha 2 Subunit - metabolism Development Female Gene Expression Regulation, Developmental Hematopoiesis Hematopoietic stem and progenitor cells Humans Liver - cytology Liver - embryology Liver - physiology Male Mice Mice, Inbred C57BL Mouse Placenta - cytology Placenta - embryology Placenta - physiology Pregnancy Promoter Regions, Genetic Runx1 Sequence Alignment Transcription, Genetic Transcriptional regulation Yolk Sac - cytology Yolk Sac - embryology Yolk Sac - physiology
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