Preparation and characterization of RGD-immobilized chitosan scaffolds

Chitosan scaffolds were modified with RGDS (Arg–Gly–Asp–Ser) in the present work via an imide-bond forming reaction between amino groups in chitosan and carboxyl groups in peptides. Successful immobilization was verified with FTIR spectroscopy, and the immobilized amount was determined to be on the...

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Veröffentlicht in:	Biomaterials 2005-06, Vol.26 (16), p.3197-3206
Hauptverfasser:	Ho, Ming-Hua, Wang, Da-Ming, Hsieh, Hsyue-Jen, Liu, Hwa-Chang, Hsien, Tzu-Yang, Lai, Juin-Yih, Hou, Lein-Tuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - chemistry Animals Biocompatibility Biocompatible Materials - chemistry Bone and Bones - cytology Bone regeneration Cell Culture Techniques - methods Cell Line, Tumor Cell Proliferation Cells, Cultured Chitin - chemistry Chitosan Chitosan - chemistry Chitosan - metabolism Culture Techniques Immunohistochemistry Microscopy, Electron, Scanning Oligopeptides - chemistry Osteoblasts - cytology Osteoblasts - metabolism Osteosarcoma Peptides - chemistry Rats RGD Scaffold Spectrophotometry, Infrared Spectroscopy, Fourier Transform Infrared - methods Time Factors Tissue engineering Tissue Engineering - methods
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