The Consequences of Insulin-Like Growth Factors/Receptors Dysfunction in Lung Cancer

The aim of this study was to investigate the consequences of insulin-like growth factors (IGF) and IGF receptor dysfunction in lung carcinomas. A correlation between increased expression (at mRNA and protein levels) for IGF-1 and IGF-1R and decreased apoptosis were found in large-cell carcinomas and...

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Veröffentlicht in:	American journal of respiratory cell and molecular biology 2005-01, Vol.32 (1), p.65-71
Hauptverfasser:	Pavelic, Jasminka, Krizanac, Simun, Kapitanovic, Sanja, Pavelic, Ljubomir, Samarzija, Miroslav, Pavicic, Fadila, Spaventi, Sime, Jakopovic, Marko, Herceg-Ivanovi, Zlata, Pavelic, Kresimir
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - metabolism Adult Aged Apoptosis - physiology Carcinoma, Large Cell - genetics Carcinoma, Large Cell - metabolism Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - metabolism Female Humans Immunohistochemistry Lung cancer Lung Neoplasms - genetics Lung Neoplasms - metabolism Male Middle Aged Receptors, Somatomedin - metabolism Somatomedins - metabolism Telomerase - metabolism Tumor Cells, Cultured
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