Interactions of alpha-, beta-, and theta-defensins with influenza A virus and surfactant protein D

We have reported that the alpha-defensins human neutrophil peptides (HNP)-1 and HNP-2 neutralize and aggregate influenza A virus (IAV) and promote uptake of IAV by neutrophils. These alpha-defensins were also shown to bind to surfactant protein (SP)-D and reduce its antiviral activity. In this study...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of immunology (1950) 2009-06, Vol.182 (12), p.7878-7887
Hauptverfasser:	Doss, Mona, White, Mitchell R, Tecle, Tesfaldet, Gantz, Donald, Crouch, Erika C, Jung, Grace, Ruchala, Piotr, Waring, Alan J, Lehrer, Robert I, Hartshorn, Kevan L
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Defensins - immunology alpha-Defensins - metabolism Animals beta-Defensins - immunology beta-Defensins - metabolism Cell Line Chickens Cricetinae Defensins - immunology Defensins - metabolism Humans Influenza A Virus, H1N1 Subtype - immunology Influenza A Virus, H1N1 Subtype - metabolism Macrophages - immunology Macrophages - metabolism Mice Microscopy, Electron, Transmission Neutrophils - immunology Neutrophils - metabolism Protein Binding Pulmonary Surfactant-Associated Protein D - immunology Pulmonary Surfactant-Associated Protein D - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!