Role of platelet-derived growth factor in airway remodeling in rhinosinusitis

The purpose of this study was to elucidate the role of platelet-derived growth factor (PDGF) in the pathogenesis of rhinosinusitis. Nasal mucosa and polyps were obtained during surgery in patients with allergic rhinitis, chronic rhinosinusitis (CRS) without asthma, and CRS with asthma. PDGF concentr...

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Veröffentlicht in:	American journal of rhinology & allergy 2009-05, Vol.23 (3), p.273-280
Hauptverfasser:	Kouzaki, Hideaki, Seno, Satoshi, Fukui, Jun, Owaki, Shigehiro, Shimizu, Takeshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Asthma - metabolism Chronic Disease Epithelial Cells - metabolism Female Humans Immunohistochemistry Macrophages - metabolism Male Middle Aged Nasal Mucosa - chemistry Nasal Polyps - metabolism Platelet-Derived Growth Factor - analysis Platelet-Derived Growth Factor - genetics Platelet-Derived Growth Factor - physiology Proto-Oncogene Proteins c-sis Rhinitis - etiology Rhinitis - metabolism RNA, Messenger - analysis Sinusitis - etiology Sinusitis - metabolism
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