Detection of classical and atypical/Nor98 scrapie by the paraffin-embedded tissue blot method

The paraffin-embedded tissue (PET) blot method was used to investigate sections of the central nervous system and lymphatic tissues from 24 cases of classical scrapie and 25 cases of atypical/Nor98 scrapie in sheep and four healthy control sheep. The PET blot detected deposits of PrPSc in the brain...

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Veröffentlicht in:	Veterinary record 2009-05, Vol.164 (22), p.677-681
Hauptverfasser:	Wemheuer, W. M., Benestad, S. L., Wrede, A., Wemheuer, W. E., Brenig, B., Bratberg, B., Schulz-Schaeffer, W. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western - methods Blotting, Western - veterinary Brain - pathology Case-Control Studies Central Nervous System - pathology Immunohistochemistry - veterinary Lymphoid Tissue - pathology Palatine Tonsil - pathology Paraffin Embedding - methods Prions - genetics Prions - isolation & purification Scrapie - genetics Scrapie - pathology Sensitivity and Specificity Sheep
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