Attitudes of high-risk women toward preimplantation genetic diagnosis
Objective To explore the knowledge and attitudes toward preimplantation genetic diagnosis (PGD) of women who have been personally affected by hereditary breast and ovarian cancer. Design A 33-item quantitative survey covering five domains, including demographics, knowledge and attitudes about PGD, u...
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| Veröffentlicht in: | Fertility and sterility 2009-06, Vol.91 (6), p.2361-2368 |
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| creator | Quinn, Gwendolyn, Ph.D Vadaparampil, Susan, Ph.D., M.P.H Wilson, Crystal, B.A King, Lindsey, M.P.H., C.H.E.S Choi, Jimin, Ph.D Miree, Cheryl, M.S Friedman, Sue, D.V.M |
| description | Objective To explore the knowledge and attitudes toward preimplantation genetic diagnosis (PGD) of women who have been personally affected by hereditary breast and ovarian cancer. Design A 33-item quantitative survey covering five domains, including demographics, knowledge and attitudes about PGD, usage of PGD, and informational needs. Setting Attendees of a national conference for individuals and families affected by hereditary breast and ovarian cancer participated in the survey. Patient(s) Not applicable. Intervention(s) Not applicable. Main Outcome Measure(s) Frequencies and proportions were summarized for all variables, and Fisher's exact tests were conducted to test association between two discrete variables. Result(s) Of the women surveyed, only 32% had ever heard of PGD before taking the survey. None of the women surveyed had actually used PGD, and 44% believed they would not use it in the future. However, 57% of attendees believed that PGD was an acceptable option for high-risk individuals, and 74% believed that high-risk individuals should be given information about PGD. Conclusion(s) Health care professionals who serve cancer patients should consider incorporating information about PGD into patient education. Further research is needed to survey physicians and genetic counselors about their knowledge and opinions of PGD. |
| doi_str_mv | 10.1016/j.fertnstert.2008.03.019 |
| format | Article |
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Design A 33-item quantitative survey covering five domains, including demographics, knowledge and attitudes about PGD, usage of PGD, and informational needs. Setting Attendees of a national conference for individuals and families affected by hereditary breast and ovarian cancer participated in the survey. Patient(s) Not applicable. Intervention(s) Not applicable. Main Outcome Measure(s) Frequencies and proportions were summarized for all variables, and Fisher's exact tests were conducted to test association between two discrete variables. Result(s) Of the women surveyed, only 32% had ever heard of PGD before taking the survey. None of the women surveyed had actually used PGD, and 44% believed they would not use it in the future. However, 57% of attendees believed that PGD was an acceptable option for high-risk individuals, and 74% believed that high-risk individuals should be given information about PGD. Conclusion(s) Health care professionals who serve cancer patients should consider incorporating information about PGD into patient education. Further research is needed to survey physicians and genetic counselors about their knowledge and opinions of PGD.</description><identifier>ISSN: 0015-0282</identifier><identifier>EISSN: 1556-5653</identifier><identifier>DOI: 10.1016/j.fertnstert.2008.03.019</identifier><identifier>PMID: 18440521</identifier><identifier>CODEN: FESTAS</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Attitude ; Biological and medical sciences ; BRCA1 or BRCA2 (BRCA1/2) ; Breast Neoplasms - genetics ; Breast Neoplasms - psychology ; Chromosome Aberrations ; Educational Status ; Europe ; Family ; Female ; Female genital diseases ; Genes, BRCA1 ; Genes, BRCA2 ; Genetic Diseases, Inborn ; Genetic Testing - psychology ; Guidelines as Topic ; Gynecology. Andrology. Obstetrics ; Health Knowledge, Attitudes, Practice ; Health Surveys ; hereditary breast and ovarian cancer ; Humans ; Internal Medicine ; Mammary gland diseases ; Marital Status ; Medical sciences ; Obstetrics and Gynecology ; Ovarian Neoplasms - genetics ; Ovarian Neoplasms - psychology ; Preimplantation Diagnosis - statistics & numerical data ; Preimplantation Diagnosis - trends ; Preimplantation genetic diagnosis ; Surveys and Questionnaires ; Tumors ; Young Adult</subject><ispartof>Fertility and sterility, 2009-06, Vol.91 (6), p.2361-2368</ispartof><rights>American Society for Reproductive Medicine</rights><rights>2009 American Society for Reproductive Medicine</rights><rights>2009 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c507t-5b505e556cf1f8bf737ca2a1fba57c6900f8a5ac97c0fb6f28ec32ab2b8693063</citedby><cites>FETCH-LOGICAL-c507t-5b505e556cf1f8bf737ca2a1fba57c6900f8a5ac97c0fb6f28ec32ab2b8693063</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0015028208005906$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21615084$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18440521$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Quinn, Gwendolyn, Ph.D</creatorcontrib><creatorcontrib>Vadaparampil, Susan, Ph.D., M.P.H</creatorcontrib><creatorcontrib>Wilson, Crystal, B.A</creatorcontrib><creatorcontrib>King, Lindsey, M.P.H., C.H.E.S</creatorcontrib><creatorcontrib>Choi, Jimin, Ph.D</creatorcontrib><creatorcontrib>Miree, Cheryl, M.S</creatorcontrib><creatorcontrib>Friedman, Sue, D.V.M</creatorcontrib><title>Attitudes of high-risk women toward preimplantation genetic diagnosis</title><title>Fertility and sterility</title><addtitle>Fertil Steril</addtitle><description>Objective To explore the knowledge and attitudes toward preimplantation genetic diagnosis (PGD) of women who have been personally affected by hereditary breast and ovarian cancer. Design A 33-item quantitative survey covering five domains, including demographics, knowledge and attitudes about PGD, usage of PGD, and informational needs. Setting Attendees of a national conference for individuals and families affected by hereditary breast and ovarian cancer participated in the survey. Patient(s) Not applicable. Intervention(s) Not applicable. Main Outcome Measure(s) Frequencies and proportions were summarized for all variables, and Fisher's exact tests were conducted to test association between two discrete variables. Result(s) Of the women surveyed, only 32% had ever heard of PGD before taking the survey. None of the women surveyed had actually used PGD, and 44% believed they would not use it in the future. However, 57% of attendees believed that PGD was an acceptable option for high-risk individuals, and 74% believed that high-risk individuals should be given information about PGD. Conclusion(s) Health care professionals who serve cancer patients should consider incorporating information about PGD into patient education. Further research is needed to survey physicians and genetic counselors about their knowledge and opinions of PGD.</description><subject>Adult</subject><subject>Attitude</subject><subject>Biological and medical sciences</subject><subject>BRCA1 or BRCA2 (BRCA1/2)</subject><subject>Breast Neoplasms - genetics</subject><subject>Breast Neoplasms - psychology</subject><subject>Chromosome Aberrations</subject><subject>Educational Status</subject><subject>Europe</subject><subject>Family</subject><subject>Female</subject><subject>Female genital diseases</subject><subject>Genes, BRCA1</subject><subject>Genes, BRCA2</subject><subject>Genetic Diseases, Inborn</subject><subject>Genetic Testing - psychology</subject><subject>Guidelines as Topic</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Health Knowledge, Attitudes, Practice</subject><subject>Health Surveys</subject><subject>hereditary breast and ovarian cancer</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Mammary gland diseases</subject><subject>Marital Status</subject><subject>Medical sciences</subject><subject>Obstetrics and Gynecology</subject><subject>Ovarian Neoplasms - genetics</subject><subject>Ovarian Neoplasms - psychology</subject><subject>Preimplantation Diagnosis - statistics & numerical data</subject><subject>Preimplantation Diagnosis - trends</subject><subject>Preimplantation genetic diagnosis</subject><subject>Surveys and Questionnaires</subject><subject>Tumors</subject><subject>Young Adult</subject><issn>0015-0282</issn><issn>1556-5653</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkcFu1DAQhi0EokvhFVAucEs6dtaOc0EqVYFKlTgAZ8txxltvE3uxnVZ9exztikqcuMxcvpn59Q0hFYWGAhUX-8ZizD7lUhsGIBtoG6D9C7KhnIuaC96-JBsAymtgkp2RNyntAUDQjr0mZ1Rut8AZ3ZDry5xdXkZMVbDVndvd1dGl--oxzOirHB51HKtDRDcfJu2zzi74aoceszPV6PTOh-TSW_LK6inhu1M_J7--XP-8-lbffv96c3V5WxsOXa75wIFjCWgstXKwXdsZzTS1g-adET2AlZpr03cG7CAsk2hapgc2SNG3INpz8vG49xDD7wVTVrNLBqcSDcOSlOhaCrxbQXkETQwpRbTqEN2s45OioFaFaq-eFapVoYJWFYVl9P3pxjLMOD4PnpwV4MMJ0MnoyUbtjUt_OUYF5SC3hft85LAYeXAYVTIOvcHRRTRZjcH9T5pP_ywxk_Ou3L3HJ0z7sERfjCuqElOgfqwvXz8OEoD3Rdkf6omqtA</recordid><startdate>20090601</startdate><enddate>20090601</enddate><creator>Quinn, Gwendolyn, Ph.D</creator><creator>Vadaparampil, Susan, Ph.D., M.P.H</creator><creator>Wilson, Crystal, B.A</creator><creator>King, Lindsey, M.P.H., C.H.E.S</creator><creator>Choi, Jimin, Ph.D</creator><creator>Miree, Cheryl, M.S</creator><creator>Friedman, Sue, D.V.M</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20090601</creationdate><title>Attitudes of high-risk women toward preimplantation genetic diagnosis</title><author>Quinn, Gwendolyn, Ph.D ; Vadaparampil, Susan, Ph.D., M.P.H ; Wilson, Crystal, B.A ; King, Lindsey, M.P.H., C.H.E.S ; Choi, Jimin, Ph.D ; Miree, Cheryl, M.S ; Friedman, Sue, D.V.M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c507t-5b505e556cf1f8bf737ca2a1fba57c6900f8a5ac97c0fb6f28ec32ab2b8693063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adult</topic><topic>Attitude</topic><topic>Biological and medical sciences</topic><topic>BRCA1 or BRCA2 (BRCA1/2)</topic><topic>Breast Neoplasms - genetics</topic><topic>Breast Neoplasms - psychology</topic><topic>Chromosome Aberrations</topic><topic>Educational Status</topic><topic>Europe</topic><topic>Family</topic><topic>Female</topic><topic>Female genital diseases</topic><topic>Genes, BRCA1</topic><topic>Genes, BRCA2</topic><topic>Genetic Diseases, Inborn</topic><topic>Genetic Testing - psychology</topic><topic>Guidelines as Topic</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Health Knowledge, Attitudes, Practice</topic><topic>Health Surveys</topic><topic>hereditary breast and ovarian cancer</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Mammary gland diseases</topic><topic>Marital Status</topic><topic>Medical sciences</topic><topic>Obstetrics and Gynecology</topic><topic>Ovarian Neoplasms - genetics</topic><topic>Ovarian Neoplasms - psychology</topic><topic>Preimplantation Diagnosis - statistics & numerical data</topic><topic>Preimplantation Diagnosis - trends</topic><topic>Preimplantation genetic diagnosis</topic><topic>Surveys and Questionnaires</topic><topic>Tumors</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Quinn, Gwendolyn, Ph.D</creatorcontrib><creatorcontrib>Vadaparampil, Susan, Ph.D., M.P.H</creatorcontrib><creatorcontrib>Wilson, Crystal, B.A</creatorcontrib><creatorcontrib>King, Lindsey, M.P.H., C.H.E.S</creatorcontrib><creatorcontrib>Choi, Jimin, Ph.D</creatorcontrib><creatorcontrib>Miree, Cheryl, M.S</creatorcontrib><creatorcontrib>Friedman, Sue, D.V.M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fertility and sterility</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Quinn, Gwendolyn, Ph.D</au><au>Vadaparampil, Susan, Ph.D., M.P.H</au><au>Wilson, Crystal, B.A</au><au>King, Lindsey, M.P.H., C.H.E.S</au><au>Choi, Jimin, Ph.D</au><au>Miree, Cheryl, M.S</au><au>Friedman, Sue, D.V.M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Attitudes of high-risk women toward preimplantation genetic diagnosis</atitle><jtitle>Fertility and sterility</jtitle><addtitle>Fertil Steril</addtitle><date>2009-06-01</date><risdate>2009</risdate><volume>91</volume><issue>6</issue><spage>2361</spage><epage>2368</epage><pages>2361-2368</pages><issn>0015-0282</issn><eissn>1556-5653</eissn><coden>FESTAS</coden><abstract>Objective To explore the knowledge and attitudes toward preimplantation genetic diagnosis (PGD) of women who have been personally affected by hereditary breast and ovarian cancer. Design A 33-item quantitative survey covering five domains, including demographics, knowledge and attitudes about PGD, usage of PGD, and informational needs. Setting Attendees of a national conference for individuals and families affected by hereditary breast and ovarian cancer participated in the survey. Patient(s) Not applicable. Intervention(s) Not applicable. Main Outcome Measure(s) Frequencies and proportions were summarized for all variables, and Fisher's exact tests were conducted to test association between two discrete variables. Result(s) Of the women surveyed, only 32% had ever heard of PGD before taking the survey. None of the women surveyed had actually used PGD, and 44% believed they would not use it in the future. However, 57% of attendees believed that PGD was an acceptable option for high-risk individuals, and 74% believed that high-risk individuals should be given information about PGD. Conclusion(s) Health care professionals who serve cancer patients should consider incorporating information about PGD into patient education. Further research is needed to survey physicians and genetic counselors about their knowledge and opinions of PGD.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>18440521</pmid><doi>10.1016/j.fertnstert.2008.03.019</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Adult Attitude Biological and medical sciences BRCA1 or BRCA2 (BRCA1/2) Breast Neoplasms - genetics Breast Neoplasms - psychology Chromosome Aberrations Educational Status Europe Family Female Female genital diseases Genes, BRCA1 Genes, BRCA2 Genetic Diseases, Inborn Genetic Testing - psychology Guidelines as Topic Gynecology. Andrology. Obstetrics Health Knowledge, Attitudes, Practice Health Surveys hereditary breast and ovarian cancer Humans Internal Medicine Mammary gland diseases Marital Status Medical sciences Obstetrics and Gynecology Ovarian Neoplasms - genetics Ovarian Neoplasms - psychology Preimplantation Diagnosis - statistics & numerical data Preimplantation Diagnosis - trends Preimplantation genetic diagnosis Surveys and Questionnaires Tumors Young Adult |
| title | Attitudes of high-risk women toward preimplantation genetic diagnosis |
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