Preparation and Evaluation of Novel Directly-Compressed Fast-Disintegrating Furosemide Tablets with Sucrose Stearic Acid Ester

Fast-disintegrating tablets of furosemide (FS) were prepared by the novel direct compression method. FS, microcrystalline cellulose (MC), croscarmellose sodium (CC), xylitol (XL) and sucrose stearic acid esters (SSEs) with an hydrophilic–lipophilic balance (HLB) of 16, 15 and 11, named S1670, S1570...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biological & pharmaceutical bulletin 2009/06/01, Vol.32(6), pp.1126-1130
Hauptverfasser:	Koseki, Takuma, Onishi, Hiraku, Takahashi, Yuri, Uchida, Minoru, Machida, Yoshiharu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Drug Compounding - methods Esters - chemistry Excipients - chemistry fast-disintegrating tablet furosemide Furosemide - blood Furosemide - chemistry Male Microscopy, Electron, Scanning plasma concentration Rats Rats, Sprague-Dawley Solubility Sucrose - analogs & derivatives Sucrose - chemistry sucrose stearic acid ester Surface Properties tablet property Tablets Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!