Antiphospholipid antibodies--our experience
Antiphospholipid antibodies (APA) have aroused multispeciality interests. In our study of 200 cases worked up for APA, we have used a few simple coagulation tests to detect lupus anticoagulant (LA) and ELISA to detect anticardiolipin antibodies. The positivity rate for LA among cases with recurrent...
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| Veröffentlicht in: | Indian journal of pathology & microbiology 2004-04, Vol.47 (2), p.174-177 |
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| container_title | Indian journal of pathology & microbiology |
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| creator | Srikrishna, Anuradha Sitalakshmi, S Devi, Shanthala Damodar, Prema Varghese, Jessy Suresh, John Mathew, Thresiamma |
| description | Antiphospholipid antibodies (APA) have aroused multispeciality interests. In our study of 200 cases worked up for APA, we have used a few simple coagulation tests to detect lupus anticoagulant (LA) and ELISA to detect anticardiolipin antibodies. The positivity rate for LA among cases with recurrent pregnancy loss was 4.16% and for aCL 20.8%. The positivity rate for LA in patients with venous thrombosis was 6.2%, in arterial thrombosis was 7.14% and in SLE patients was 58.3%. In conclusion APAs are to be looked for in cases of recurrent pregnancy loss, thrombosis in people < 45 years of age without risk factors and SLE patients to assess the thrombotic risk and to decide on anti coagulant therapy for further management. |
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| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Abortion, Habitual - immunology Adult Antibodies, Anticardiolipin - blood Antibodies, Antiphospholipid - blood Female Humans Lupus Coagulation Inhibitor - blood Lupus Erythematosus, Systemic - immunology Male Middle Aged Pre-Eclampsia - immunology Pregnancy Thrombosis - immunology |
| title | Antiphospholipid antibodies--our experience |
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