New Photoproducts from Irradiation of NADH with Near-UV Light
Adenosine 5′‐diphosphoribose (ADPR) and a second compound, which may be nicotinamide, are the newly discovered photoproducts resulting from irradiation of β‐nicotinamide adenine dinucleotide (β‐NADH) in the wavelength range of 300–400 nm under oxygen‐poor conditions. Both products emerge there even...
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Veröffentlicht in: | Chemistry & biodiversity 2004-10, Vol.1 (10), p.1487-1497 |
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creator | Vitinius, Ute Schaffner, Kurt Demuth, Martin Heibel, Marija Selbach, Horst |
description | Adenosine 5′‐diphosphoribose (ADPR) and a second compound, which may be nicotinamide, are the newly discovered photoproducts resulting from irradiation of β‐nicotinamide adenine dinucleotide (β‐NADH) in the wavelength range of 300–400 nm under oxygen‐poor conditions. Both products emerge there even exclusively, whereas, at higher oxygen concentrations, the oxidized form of nicotinamide adenine dinucleotide (NAD+) is additionally formed, although still as a minor product. The development of ADPR and NAD+ is clearly oxygen‐dependent, while, for the formation of the second photoproduct, small quantities of oxygen appear to be sufficient. |
doi_str_mv | 10.1002/cbdv.200490109 |
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Both products emerge there even exclusively, whereas, at higher oxygen concentrations, the oxidized form of nicotinamide adenine dinucleotide (NAD+) is additionally formed, although still as a minor product. 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Both products emerge there even exclusively, whereas, at higher oxygen concentrations, the oxidized form of nicotinamide adenine dinucleotide (NAD+) is additionally formed, although still as a minor product. The development of ADPR and NAD+ is clearly oxygen‐dependent, while, for the formation of the second photoproduct, small quantities of oxygen appear to be sufficient.</description><subject>NAD - analysis</subject><subject>NAD - chemistry</subject><subject>NAD - radiation effects</subject><subject>Photochemistry</subject><subject>Ultraviolet Rays</subject><issn>1612-1872</issn><issn>1612-1880</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtTwjAUhTOOjiC6del05a6YF02ycIEgD2WqC8FlJk1SqVKKSRH595Ypg-5c3Tt3vnPm3APAJYJtBCG-0Yn5amMIqYAIiiPQRBHCIeIcHh92hhvgzPv3iq_u_BQ0EEMCMYGb4Da2m-B5XpTFyhVmrUsfpK7Ig7FzymSqzIplUKRB3O2Pgk1WzoPYKhdOZ8Eke5uX5-AkVQtvL_azBaaD-5feKJw8Dce97iTUhCMRUqGxNQaxKKGCcJJwYRjnNIkinkJCjNYp7TAolMaUcsEUpJymlBlhEDYpaYHr2rcK-bm2vpR55rVdLNTSFmsvI4YF7RBUge0a1K7w3tlUrlyWK7eVCMpdYXJXmDwUVgmu9s7rJLfmF983VAGiBjbZwm7_sZO9u_7sr3lYazNf2u-DVrmPKjFhHfkaDyUeDFj1-6N8ID-FW4Qy</recordid><startdate>200410</startdate><enddate>200410</enddate><creator>Vitinius, Ute</creator><creator>Schaffner, Kurt</creator><creator>Demuth, Martin</creator><creator>Heibel, Marija</creator><creator>Selbach, Horst</creator><general>WILEY-VCH Verlag</general><general>WILEY‐VCH Verlag</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200410</creationdate><title>New Photoproducts from Irradiation of NADH with Near-UV Light</title><author>Vitinius, Ute ; Schaffner, Kurt ; Demuth, Martin ; Heibel, Marija ; Selbach, Horst</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3819-49c2edd176b49383b89d7884b668f033dccf45709ac244897a0484f47d9d12df3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>NAD - analysis</topic><topic>NAD - chemistry</topic><topic>NAD - radiation effects</topic><topic>Photochemistry</topic><topic>Ultraviolet Rays</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vitinius, Ute</creatorcontrib><creatorcontrib>Schaffner, Kurt</creatorcontrib><creatorcontrib>Demuth, Martin</creatorcontrib><creatorcontrib>Heibel, Marija</creatorcontrib><creatorcontrib>Selbach, Horst</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Chemistry & biodiversity</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vitinius, Ute</au><au>Schaffner, Kurt</au><au>Demuth, Martin</au><au>Heibel, Marija</au><au>Selbach, Horst</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>New Photoproducts from Irradiation of NADH with Near-UV Light</atitle><jtitle>Chemistry & biodiversity</jtitle><addtitle>Chemistry & Biodiversity</addtitle><date>2004-10</date><risdate>2004</risdate><volume>1</volume><issue>10</issue><spage>1487</spage><epage>1497</epage><pages>1487-1497</pages><issn>1612-1872</issn><eissn>1612-1880</eissn><abstract>Adenosine 5′‐diphosphoribose (ADPR) and a second compound, which may be nicotinamide, are the newly discovered photoproducts resulting from irradiation of β‐nicotinamide adenine dinucleotide (β‐NADH) in the wavelength range of 300–400 nm under oxygen‐poor conditions. Both products emerge there even exclusively, whereas, at higher oxygen concentrations, the oxidized form of nicotinamide adenine dinucleotide (NAD+) is additionally formed, although still as a minor product. The development of ADPR and NAD+ is clearly oxygen‐dependent, while, for the formation of the second photoproduct, small quantities of oxygen appear to be sufficient.</abstract><cop>Zürich</cop><pub>WILEY-VCH Verlag</pub><pmid>17191792</pmid><doi>10.1002/cbdv.200490109</doi><tpages>11</tpages></addata></record> |
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subjects | NAD - analysis NAD - chemistry NAD - radiation effects Photochemistry Ultraviolet Rays |
title | New Photoproducts from Irradiation of NADH with Near-UV Light |
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