New Photoproducts from Irradiation of NADH with Near-UV Light

Adenosine 5′‐diphosphoribose (ADPR) and a second compound, which may be nicotinamide, are the newly discovered photoproducts resulting from irradiation of β‐nicotinamide adenine dinucleotide (β‐NADH) in the wavelength range of 300–400 nm under oxygen‐poor conditions. Both products emerge there even...

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Veröffentlicht in:Chemistry & biodiversity 2004-10, Vol.1 (10), p.1487-1497
Hauptverfasser: Vitinius, Ute, Schaffner, Kurt, Demuth, Martin, Heibel, Marija, Selbach, Horst
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container_issue 10
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container_title Chemistry & biodiversity
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creator Vitinius, Ute
Schaffner, Kurt
Demuth, Martin
Heibel, Marija
Selbach, Horst
description Adenosine 5′‐diphosphoribose (ADPR) and a second compound, which may be nicotinamide, are the newly discovered photoproducts resulting from irradiation of β‐nicotinamide adenine dinucleotide (β‐NADH) in the wavelength range of 300–400 nm under oxygen‐poor conditions. Both products emerge there even exclusively, whereas, at higher oxygen concentrations, the oxidized form of nicotinamide adenine dinucleotide (NAD+) is additionally formed, although still as a minor product. The development of ADPR and NAD+ is clearly oxygen‐dependent, while, for the formation of the second photoproduct, small quantities of oxygen appear to be sufficient.
doi_str_mv 10.1002/cbdv.200490109
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subjects NAD - analysis
NAD - chemistry
NAD - radiation effects
Photochemistry
Ultraviolet Rays
title New Photoproducts from Irradiation of NADH with Near-UV Light
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