Aldosterone blockade attenuates development of an electrophysiological substrate associated with ventricular tachyarrhythmias in heart failure

Background Aldosterone blockade reduces sudden cardiac death in heart failure, but the underlying mechanism is unclear. Objective This study's aim was to determine whether chronic eplerenone treatment protects against detrimental ventricular electrical remodeling and development of an arrhythmo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Heart rhythm 2009-06, Vol.6 (6), p.776-783
Hauptverfasser:	Stambler, Bruce S., MD, FHRS, Laurita, Kenneth R., PhD, Shroff, Sunil C., MD, Hoeker, Gregory, BS, Martovitz, Nichole L
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldosterone Animals Cardiovascular Disease Models, Animal Dogs Electrocardiography Electrogram Electrophysiology Eplerenone Heart failure Heart Failure - complications Heart Failure - physiopathology Mineralocorticoid Receptor Antagonists - pharmacology Spironolactone - analogs & derivatives Spironolactone - pharmacology Sudden death Tachyarrhythmias Tachycardia, Ventricular - etiology Tachycardia, Ventricular - physiopathology Ventricular Remodeling - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!