Endothelin-1 Regulates Protein Kinase C Isoforms Differently in Smooth Muscle Cells and in Cardiomyocytes

Endothelin-1 (ET-1) is known to increase the mitotic response of different growth factors but also to different vasoactive hormones already at threshold concentrations. The aim of this study was to investigate the influence of chronic elevated ET-1 concentrations on protein kinase C (PKC) isoforms i...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 2004-11, Vol.44 Suppl 1 (Supplement 1), p.S301-S303
Hauptverfasser:	Wolf, Sabine C, Brodbeck, Christian, Sauter, Gabriele, Risler, Teut, Brehm, Bernhard R
Format:	Artikel
Sprache:	eng
Schlagworte:	Active Transport, Cell Nucleus Angiotensin II - metabolism Animals Cell Line Cytoplasm - enzymology Endothelin-1 - administration & dosage Endothelin-1 - metabolism Infusions, Parenteral Isoenzymes Male Muscle, Smooth, Vascular - enzymology Myocytes, Cardiac - enzymology Myocytes, Smooth Muscle - enzymology Protein Kinase C-alpha - metabolism Protein Kinase C-delta - metabolism Protein Kinase C-epsilon - metabolism Rats Time Factors Up-Regulation
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