Role of the orbital cortex and of the serotonergic system in a rat model of obsessive compulsive disorder

The serotonergic system and the orbitofrontal cortex have been consistently implicated in the pathophysiology of obsessive compulsive disorder. Yet, the relations between these two systems and the ways they interact in producing obsessions and compulsions are poorly understood. The present study tes...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience 2005, Vol.130 (1), p.25-36
Hauptverfasser:	Joel, D., Doljansky, J., Roz, N., Rehavi, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidepressive Agents - pharmacology Antidepressive Agents - therapeutic use Behavior, Animal Biological and medical sciences Conditioning, Operant - drug effects Conditioning, Operant - physiology Disease Models, Animal Dose-Response Relationship, Drug extinction Extinction, Psychological - drug effects Frontal Lobe - drug effects Frontal Lobe - metabolism Frontal Lobe - pathology Frontal Lobe - physiopathology Fundamental and applied biological sciences. Psychology Imipramine - pharmacokinetics Male obsessive compulsive disorder (OCD) Obsessive-Compulsive Disorder - drug therapy Obsessive-Compulsive Disorder - metabolism Obsessive-Compulsive Disorder - pathology Obsessive-Compulsive Disorder - physiopathology orbitofrontal cortex Paroxetine - pharmacology Paroxetine - therapeutic use post-training signal attenuation Protein Binding - drug effects Protein Binding - physiology Random Allocation Rats Rats, Wistar Serotonin - metabolism serotonin transporter Tritium - pharmacokinetics Vertebrates: nervous system and sense organs ‘compulsive’ lever-pressing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!