Development of a lipoprotein based molecular imaging MR contrast agent for the noninvasive detection of early atherosclerotic disease

Currently there are no clinically available means of noninvasively detecting early atherosclerotic disease because these lesions are characterized by an accumulation of extracellular lipid and foam cells, but a lack of significant wall thickening or architectural distortion. We hypothesize that a pa...

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Veröffentlicht in:	The International Journal of Cardiovascular Imaging 2004-12, Vol.20 (6), p.561-567
Hauptverfasser:	Mitsumori, L M, Ricks, J L, Rosenfeld, M E, Schmiedl, U P, Yuan, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arteriosclerosis - diagnosis Cell Line, Tumor Chromatography, Gel Contrast Media - chemical synthesis Feasibility Studies Foam Cells - pathology Hydrophobic and Hydrophilic Interactions Lipoproteins, LDL Magnetic Resonance Imaging - methods Manganese Mass Spectrometry Mesoporphyrins Mice
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