Inhibitory effects of flavonoids on TNF-α-induced IL-8 gene expression in HEK 293 cells

Due to their multiple biological activities, flavonoids have gained attention as potentially useful therapeutics for a variety of diseases including cancer, cardiovascular diseases, and autoimmune diseases. In this study, we demonstrated that several flavonoids, including kaempferol, quercetin, fise...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	BMB reports 2009-05, Vol.42 (5), p.265-270
Hauptverfasser:	Lee, S.H. (Hallym University, Chuncheon, Republic of Korea), Kim, Y.J. (Hallym University, Chuncheon, Republic of Korea), Kwon, S.H. (Hallym University, Chuncheon, Republic of Korea), Lee, Y.H. (Chungbuk National University, Cheongju, Republic of Korea), Choi, S.Y. (Hallym University, Chuncheon, Republic of Korea), Park, J.S. (Hallym University, Chuncheon, Republic of Korea), Kwon, H.J. (Hallym University, Chuncheon, Republic of Korea), E-mail: hjookwon@hallym.ac.kr
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cell Survival - drug effects FLAVONOIDE FLAVONOIDES FLAVONOIDS Flavonoids - metabolism Flavonoids - pharmacology Gene Expression Regulation - drug effects Humans IL-8 Inflammation - immunology Interleukin-8 - genetics Interleukin-8 - metabolism KAEMPFEROL NF-kappa B NF-kappa B - metabolism Promoter Regions, Genetic Reactive Oxygen Species - metabolism ROS Tumor Necrosis Factor-alpha - genetics Tumor Necrosis Factor-alpha - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!