Simultaneous assessment of left-ventricular infarction size, function and tissue viability in a murine model of myocardial infarction by cardiac manganese-enhanced magnetic resonance imaging (MEMRI)

Owing to its signal‐enhancing characteristics in viable well‐perfused tissue, divalent manganese (Mn2+) has been used as a myocardial imaging contrast agent. Because Mn2+ can enter excitable cells through the voltage‐gated L‐type calcium channels, manganese‐enhanced MRI (MEMRI) has been used to dete...

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Veröffentlicht in:	NMR in biomedicine 2004-12, Vol.17 (8), p.620-626
Hauptverfasser:	Hu, Tom C.-C., Bao, Weike, Lenhard, Stephen C., Schaeffer, Thomas R., Yue, Tian-li, Willette, Robert N., Jucker, Beat M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals cardiac MRI Contrast Media heart Image Enhancement - methods Image Interpretation, Computer-Assisted - methods Magnetic Resonance Imaging - methods Manganese Mice Mice, Inbred ICR mouse myocardial infarction Myocardial Infarction - complications Myocardial Infarction - diagnosis Myocardial Infarction - metabolism Severity of Illness Index Tissue Survival Ventricular Dysfunction, Left - diagnosis Ventricular Dysfunction, Left - etiology Ventricular Dysfunction, Left - metabolism
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