Up-regulation of syntaxin1 in ischemic cortex after permanent focal ischemia in rats

Abstract Syntaxin1 and synaptotagmin are located in the pre-synaptic terminals and play central roles in Ca2+ -triggered neurotransmitter release. Because excessive synaptic transmission has been implicated in neuronal cell death after ischemia, we investigated the effects of cerebral ischemia on th...

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Veröffentlicht in:	Brain research 2009-05, Vol.1272, p.52-61
Hauptverfasser:	Cao, Fang, Hata, Ryuji, Zhu, Pengxiang, Niinobe, Michinobu, Sakanaka, Masahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Biological and medical sciences Calcium-Binding Proteins - metabolism Cerebral Cortex - metabolism Cerebral Cortex - physiopathology Cerebral ischemia Disease Models, Animal Glial Fibrillary Acidic Protein - metabolism Infarction, Middle Cerebral Artery - pathology Male Medical sciences Microfilament Proteins Microtubule-Associated Proteins - metabolism Neurology Rats Rats, Inbred SHR SNARE Synaptotagmin Synaptotagmins - metabolism Syntaxin 1 - metabolism Up-Regulation - physiology Vascular diseases and vascular malformations of the nervous system
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