A Case of Systemic Amyloidosis Following Ankylosing Spondylitis Associated With Congestive Heart Failure

Secondary (amyloid A [AA]) amyloidosis is a systemic disease characterized by amyloid deposition in many organs, leading to impaired function. Although cardiac involvement may occur with AA amyloidosis, significant deposition of amyloid in the heart is considered an infrequent observation and is rar...

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Veröffentlicht in:Journal of the American Society of Echocardiography 2009-05, Vol.22 (5), p.542.e5-542.e7
Hauptverfasser: Ha, Sang Jin, MD, Kim, Woo-Shik, MD, PhD, Hwang, Seung-Joon, MD, Woo, Jong Shin, MD, Shon, Il Seok, MD, PhD, Bae, Jong-Hoa, MD, PhD, Kim, Kwon Sam, MD, PhD
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container_end_page 542.e7
container_issue 5
container_start_page 542.e5
container_title Journal of the American Society of Echocardiography
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creator Ha, Sang Jin, MD
Kim, Woo-Shik, MD, PhD
Hwang, Seung-Joon, MD
Woo, Jong Shin, MD
Shon, Il Seok, MD, PhD
Bae, Jong-Hoa, MD, PhD
Kim, Kwon Sam, MD, PhD
description Secondary (amyloid A [AA]) amyloidosis is a systemic disease characterized by amyloid deposition in many organs, leading to impaired function. Although cardiac involvement may occur with AA amyloidosis, significant deposition of amyloid in the heart is considered an infrequent observation and is rarely the cause of death. It occurs in 5% of patients with poorly controlled chronic inflammatory disease, mainly rheumatoid arthritis, ankylosing spondylitis, and familial Mediterranean fever. The authors report a case of AA amyloidosis diagnosed by rectal and skin biopsies, with cardiac involvement demonstrated by typical echocardiographic features in the presence of low voltage on electrocardiography.
doi_str_mv 10.1016/j.echo.2009.01.022
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subjects Amyloidosis - diagnostic imaging
Amyloidosis - etiology
Ankylosing spondylitis
Cardiovascular
Congestive heart failure
Echocardiography
Heart Failure - complications
Heart Failure - diagnostic imaging
Humans
Male
Middle Aged
Rectal biopsy
Spondylitis, Ankylosing - complications
Spondylitis, Ankylosing - diagnostic imaging
Systemic amyloidosis
Ultrasonography
title A Case of Systemic Amyloidosis Following Ankylosing Spondylitis Associated With Congestive Heart Failure
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