Grey-box modelling of pharmacokinetic/pharmacodynamic systems

Grey-box pharmacokinetic/pharmacodynamic (PK/PD) modelling is presented as a promising way of modelling PK/PD systems. The concept behind grey-box modelling is based on combining physiological knowledge along with information from data in the estimation of model parameters. Grey-box modelling consis...

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Veröffentlicht in:	Journal of pharmacokinetics and pharmacodynamics 2004-10, Vol.31 (5), p.401-417
Hauptverfasser:	TORNØE, Christoffer W, JACOBSEN, Judith L, PEDERSEN, Oluf, HANSEN, Torben, MADSEN, Henrik
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood Glucose - drug effects Blood Glucose - metabolism Blood Glucose - physiology General pharmacology Glucose Tolerance Test - statistics & numerical data Humans Insulin - pharmacology Medical sciences Models, Biological Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology. Drug treatments Stochastic Processes
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