Uncoupling of flow and metabolism by chloral hydrate: a rat in-vivo autoradiographic study

General anesthesia is commonly used in experiments; however, its effects on cerebral circulation remain unknown. We measured cerebral blood flow using N-isopropyl[methyl 1,3-C] p-iodoamphetamine (C-IMP) and glucose utilization using 2-[1-C] deoxy-D-glucose during general anesthesia with pentobarbita...

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Veröffentlicht in:	Neuroreport 2009-02, Vol.20 (3), p.219-222
Hauptverfasser:	Uematsu, Miki, Takasawa, Masashi, Hosoi, Rie, Inoue, Osamu
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthetics. Neuromuscular blocking agents Animals Autoradiography - methods Biological and medical sciences Brain - blood supply Brain - drug effects Brain - metabolism Brain Mapping - methods Carbon Radioisotopes Cerebral Arteries - drug effects Cerebral Arteries - physiology Cerebrovascular Circulation - drug effects Cerebrovascular Circulation - physiology Chloral Hydrate - pharmacology Deoxyglucose Energy Metabolism - drug effects Energy Metabolism - physiology Glucose - metabolism Hypnotics and Sedatives - pharmacology Iofetamine Male Medical sciences Neuropharmacology Pentobarbital - pharmacology Pharmacology. Drug treatments Rats Rats, Wistar
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