Functional Haplotypes That Produce Normal Ficolin-2 Levels Protect against Clinical Leprosy

Host factors have been shown to play a significant role in the susceptibility to and clinical outcome of leprosy. Here, we analyze polymorphisms of the gene encoding ficolin-2 (FCN2) which is a soluble pattern-recognition molecule. A total of 158 patients with leprosy and 210 healthy control subject...

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Veröffentlicht in:	The Journal of infectious diseases 2009-03, Vol.199 (6), p.801-804
Hauptverfasser:	de Messias-Reason, Iara, Kremsner, Peter G., Kun, Jürgen F. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Bacteria Bacterial diseases Biological and medical sciences Chromosome Mapping Disease susceptibility DNA Primers Exons Ficolins Fundamental and applied biological sciences. Psychology Genes, Dominant Genes, Recessive Haplotypes Human bacterial diseases Humans IgA glomerulonephritis Infectious diseases Lectins Lectins - genetics Lectins - immunology Leprosy Leprosy - genetics Leprosy - immunology Leprosy - prevention & control Medical genetics Medical sciences Microbiology Polymorphism, Genetic Promoter Regions, Genetic Reference Values Respiratory diseases Tropical bacterial diseases Tuberculosis
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