Developing a Confocal Acoustic Holography Microscope for non-invasive 3D temperature and composition measurements

A Confocal Acoustic Holography Microscope (CAHM) has been designed, simulated and partially verified experimentally to take holograms for non-invasive, three-dimensional measurements of a specimen's refractive indices from one view point. The designed and simulated prototype CAHM used a frequen...

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Veröffentlicht in:Ultramicroscopy 2009-06, Vol.109 (7), p.830-836
Hauptverfasser: Herring, Rodney A., Jacquemin, Peter, Sawicka, Barbara D., Atalick, Stefan
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container_title Ultramicroscopy
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creator Herring, Rodney A.
Jacquemin, Peter
Sawicka, Barbara D.
Atalick, Stefan
description A Confocal Acoustic Holography Microscope (CAHM) has been designed, simulated and partially verified experimentally to take holograms for non-invasive, three-dimensional measurements of a specimen's refractive indices from one view point. The designed and simulated prototype CAHM used a frequency of 2.25 MHz and measured sound speed changes of 16 m/s, temperature changes of 5 °C and had a spatial resolution of 660 μm. With future improvements utilizing the latest technologies such as two-dimensional array detectors, Micro-Electro-Mechanical Systems (MEMS), and acoustic lenses, resolutions of 1 m/s, 0.5 °C, and 150 μm are expected. The CAHM is expected to have many useful applications, including non-invasive mass and heat transfer measurements in fluids and materials and as a medical diagnostic tool to non-intrusively visualize compositions and temperatures within the human body.
doi_str_mv 10.1016/j.ultramic.2009.03.027
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Acoustic beams
Acoustics
Body Composition
Body Temperature
Computer Simulation
Confocal
Equipment Design
Holography
Holography - instrumentation
Holography - methods
Humans
Imaging, Three-Dimensional
Microscopy
Microscopy, Confocal - instrumentation
Microscopy, Confocal - methods
Microscopy, Interference - instrumentation
Microscopy, Interference - methods
title Developing a Confocal Acoustic Holography Microscope for non-invasive 3D temperature and composition measurements
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