“On‐Off” Multivalent Recognition: Degradable Dendrons for Temporary High‐Affinity DNA Binding

Now you bind it—now you don't! Chemical degradation of a dendritic scaffold allows multivalent interactions with DNA to be “switched off” as the multivalent array of ligands breaks down into smaller fragments, offering an approach by which a molecule can be temporarily endowed with high affinit...

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Veröffentlicht in:	Angewandte Chemie International Edition 2009-05, Vol.48 (22), p.4047-4051
Hauptverfasser:	Welsh, Daniel J., Jones, Simon P., Smith, David K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals biodegradable compounds biological activity Cattle Dendrimers - chemistry dendrons DNA DNA - chemistry supramolecular chemistry
Online-Zugang:	Volltext
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