Genome-wide analysis of DHEA- and DHT-induced gene expression in mouse hypothalamus and hippocampus

Dehydroepiandrosterone (DHEA) is the most abundant steroid in humans and a multi-functional neuroactive steroid that has been implicated in a variety of biological effects in both the periphery and central nervous system. Mechanistic studies of DHEA in the periphery have emphasized its role as a pro...

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Veröffentlicht in:	The Journal of steroid biochemistry and molecular biology 2009-04, Vol.114 (3), p.135-143
Hauptverfasser:	Mo, Qianxing, Lu, Shifang, Garippa, Carrie, Brownstein, Michael J., Simon, Neal G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgen receptor Animals Apoptosis - genetics Appetite - genetics Biological and medical sciences Cell Survival - genetics CNS Dehydroepiandrosterone (DHEA) Dehydroepiandrosterone - pharmacology Dihydrotestosterone - pharmacology Energy Metabolism - genetics Female Fundamental and applied biological sciences. Psychology Gene Expression Profiling Gene Expression Regulation - drug effects Genome Genomics Hippocampus - drug effects Hippocampus - metabolism Hypothalamus - drug effects Hypothalamus - metabolism Mechanism of action Mice Mice, Inbred Strains Receptors, Androgen Steroid hormones. Cholecalciferol derivatives Vertebrates: endocrinology
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