Improvement of lipid profile is accompanied by atheroprotective alterations in high‐density lipoprotein composition upon tumor necrosis factor blockade: A prospective cohort study in ankylosing spondylitis

Objective Cardiovascular mortality is increased in ankylosing spondylitis (AS), and inflammation plays an important role. Inflammation deteriorates the lipid profile and alters high‐density lipoprotein cholesterol (HDL‐c) composition, reflected by increased concentrations of serum amyloid A (SAA) wi...

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Veröffentlicht in:	Arthritis and rheumatism 2009-05, Vol.60 (5), p.1324-1330
Hauptverfasser:	van Eijk, I. C., de Vries, M. K., Levels, J. H. M., Peters, M. J. L., Huizer, E. E., Dijkmans, B. A. C., van der Horst‐Bruinsma, I. E., Hazenberg, B. P. C., van de Stadt, R. J., Wolbink, G. J., Nurmohamed, M. T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Apolipoprotein A-I - blood Apolipoproteins B - blood Biological and medical sciences Blood Sedimentation C-Reactive Protein - analysis Cardiovascular Diseases - blood Cholesterol, HDL - blood Cohort Studies Diseases of the osteoarticular system Diseases of the spine Etanercept Female Humans Immunoglobulin G - pharmacology Inflammatory joint diseases Male Medical sciences Prospective Studies Receptors, Tumor Necrosis Factor Serum Amyloid A Protein - analysis Spondylitis, Ankylosing - blood Tumor Necrosis Factor-alpha - antagonists & inhibitors
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