Increased frequency of α-synuclein in the substantia nigra in human immunodeficiency virus infection

The frequency of neurodegenerative markers among long surviving human immunodeficiency virus (HIV)-infected individuals is unknown, therefore, the present study investigated the frequency of α-synuclein, β-amyloid, and HIV-associated brain pathology in the brains of older HIV-infected individuals. W...

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Veröffentlicht in:	Journal of neurovirology 2009, Vol.15 (2), p.131-138
Hauptverfasser:	Khanlou, Negar, Moore, David J., Chana, Gursharan, Cherner, Mariana, Lazzaretto, Deborah, Dawes, Sharron, Grant, Igor, Masliah, Eliezer, Everall, Ian P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Aged alpha-Synuclein - biosynthesis Amyloid beta-Peptides - biosynthesis Biological and medical sciences Biomarkers Biomedical and Life Sciences Biomedicine Female HIV HIV Infections - complications HIV Infections - metabolism Human viral diseases Humans Immunohistochemistry Immunology Infectious Diseases Male Medical sciences Middle Aged Neurodegenerative Diseases - etiology Neurodegenerative Diseases - metabolism Neurology Neurosciences Substantia Nigra - metabolism Substantia Nigra - pathology Up-Regulation Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral diseases of the nervous system Virology
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