Specificity of postsynaptic excitations of different sensory modality in neurons of edible snail during learning

The development of sensitization in edible snails during intracellular injection of oligonucleotides specifically inhibiting C/EBP transcription factors results in selective suppression of synaptic facilitation in responses of LPl1 neurons evoked by chemical stimulation of the head. At the same time...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2004-11, Vol.138 (5), p.429-432
Hauptverfasser: Nikitin, V P, Sudakov, K V, Sherstnev, V V
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container_title Bulletin of experimental biology and medicine
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creator Nikitin, V P
Sudakov, K V
Sherstnev, V V
description The development of sensitization in edible snails during intracellular injection of oligonucleotides specifically inhibiting C/EBP transcription factors results in selective suppression of synaptic facilitation in responses of LPl1 neurons evoked by chemical stimulation of the head. At the same time, facilitation of the responses to tactile stimulation of the head or foot developed as in control sensitized animals. The data are interpreted from the viewpoint of P. K. Anokhin hypothesis that integrative function of cerebral neurons involved in construction of biologic functional systems is based on peculiar pre- and postsynaptic chemical processes selectively projected onto the genome of neural cell.
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subjects Animals
CCAAT-Enhancer-Binding Proteins - genetics
CCAAT-Enhancer-Binding Proteins - physiology
Electric Stimulation
Evoked Potentials, Somatosensory - drug effects
Evoked Potentials, Somatosensory - physiology
Excitatory Postsynaptic Potentials - drug effects
Excitatory Postsynaptic Potentials - physiology
Helix (Snails) - physiology
Learning - physiology
Neurons, Afferent - drug effects
Neurons, Afferent - physiology
Quinine - pharmacology
title Specificity of postsynaptic excitations of different sensory modality in neurons of edible snail during learning
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