Specificity of postsynaptic excitations of different sensory modality in neurons of edible snail during learning
The development of sensitization in edible snails during intracellular injection of oligonucleotides specifically inhibiting C/EBP transcription factors results in selective suppression of synaptic facilitation in responses of LPl1 neurons evoked by chemical stimulation of the head. At the same time...
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Veröffentlicht in: | Bulletin of experimental biology and medicine 2004-11, Vol.138 (5), p.429-432 |
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creator | Nikitin, V P Sudakov, K V Sherstnev, V V |
description | The development of sensitization in edible snails during intracellular injection of oligonucleotides specifically inhibiting C/EBP transcription factors results in selective suppression of synaptic facilitation in responses of LPl1 neurons evoked by chemical stimulation of the head. At the same time, facilitation of the responses to tactile stimulation of the head or foot developed as in control sensitized animals. The data are interpreted from the viewpoint of P. K. Anokhin hypothesis that integrative function of cerebral neurons involved in construction of biologic functional systems is based on peculiar pre- and postsynaptic chemical processes selectively projected onto the genome of neural cell. |
doi_str_mv | 10.1007/s10517-005-0061-4 |
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subjects | Animals CCAAT-Enhancer-Binding Proteins - genetics CCAAT-Enhancer-Binding Proteins - physiology Electric Stimulation Evoked Potentials, Somatosensory - drug effects Evoked Potentials, Somatosensory - physiology Excitatory Postsynaptic Potentials - drug effects Excitatory Postsynaptic Potentials - physiology Helix (Snails) - physiology Learning - physiology Neurons, Afferent - drug effects Neurons, Afferent - physiology Quinine - pharmacology |
title | Specificity of postsynaptic excitations of different sensory modality in neurons of edible snail during learning |
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