DPPH Free Radical Scavenger Components from the Fruits of Alpinia rafflesiana Wall. ex. Bak. (Zingiberaceae)
The methanol extract of the dried ripe fruits of Alpinia rafflesiana was investigated for its DPPH free radical scavenger constituents. 2′,3′,4′,6′-Tetrahydroxychalcone (7), which has never been isolated from natural sources was found to be most active as a DPPH free radical scavenger with the IC va...
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| Veröffentlicht in: | Zeitschrift für Naturforschung C. A journal of biosciences 2004-11, Vol.59 (11), p.811-815 |
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| container_title | Zeitschrift für Naturforschung C. A journal of biosciences |
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| creator | Mohamad, Habsah Abas, Faridah Permana, Dharma Lajis, Nordin H. Ali, Abdul Manaf Sukari, Mohd Aspollah Hin, Taufiq Y. Y. Kikuzaki, Hiroe Nakatani, Nobuji |
| description | The methanol extract of the dried ripe fruits of Alpinia rafflesiana was investigated for its DPPH free radical scavenger constituents. 2′,3′,4′,6′-Tetrahydroxychalcone (7), which has never been isolated from natural sources was found to be most active as a DPPH free radical scavenger with the IC
value of 55 μᴍ. Other known compounds isolated from this species include 5,6-dehydrokawain (1), flavokawin B (2), 1,7-diphenyl-5-hydroxy-6-hepten-3-one (3), (-)-pinocembrin (4), cardamonin (5) and (-)-pinostrobin (6). The DPPH free radical scavenger compounds were detected using TLC autographic analysis. The percentage inhibition of DPPH free radical scavenging activity was measured on isolates (5-7) using colorimetric analysis. |
| doi_str_mv | 10.1515/znc-2004-11-1208 |
| format | Article |
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value of 55 μᴍ. Other known compounds isolated from this species include 5,6-dehydrokawain (1), flavokawin B (2), 1,7-diphenyl-5-hydroxy-6-hepten-3-one (3), (-)-pinocembrin (4), cardamonin (5) and (-)-pinostrobin (6). The DPPH free radical scavenger compounds were detected using TLC autographic analysis. The percentage inhibition of DPPH free radical scavenging activity was measured on isolates (5-7) using colorimetric analysis.</description><identifier>ISSN: 0939-5075</identifier><identifier>EISSN: 1865-7125</identifier><identifier>DOI: 10.1515/znc-2004-11-1208</identifier><identifier>PMID: 15666539</identifier><language>eng</language><publisher>Germany: Verlag der Zeitschrift für Naturforschung</publisher><subject>2′,3′,4′,6′-Tetrahydroxychalcone ; Alpinia - chemistry ; Alpinia rafflesiana ; Biphenyl Compounds - isolation & purification ; Biphenyl Compounds - pharmacology ; Chalcones - chemistry ; Chalcones - isolation & purification ; Free Radical Scavenger Activity ; Free Radical Scavengers - isolation & purification ; Free Radical Scavengers - pharmacology ; Hydrazines - isolation & purification ; Hydrazines - pharmacology ; Magnetic Resonance Spectroscopy ; Malaysia ; Models, Molecular ; Molecular Structure ; Picrates ; Seeds - chemistry ; Spectroscopy, Fourier Transform Infrared</subject><ispartof>Zeitschrift für Naturforschung C. A journal of biosciences, 2004-11, Vol.59 (11), p.811-815</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c398t-e4d83f9fab65abe15cd576fe928dd4b4cc560339d0434ee6cf8d398d5e5485763</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15666539$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mohamad, Habsah</creatorcontrib><creatorcontrib>Abas, Faridah</creatorcontrib><creatorcontrib>Permana, Dharma</creatorcontrib><creatorcontrib>Lajis, Nordin H.</creatorcontrib><creatorcontrib>Ali, Abdul Manaf</creatorcontrib><creatorcontrib>Sukari, Mohd Aspollah</creatorcontrib><creatorcontrib>Hin, Taufiq Y. Y.</creatorcontrib><creatorcontrib>Kikuzaki, Hiroe</creatorcontrib><creatorcontrib>Nakatani, Nobuji</creatorcontrib><title>DPPH Free Radical Scavenger Components from the Fruits of Alpinia rafflesiana Wall. ex. Bak. (Zingiberaceae)</title><title>Zeitschrift für Naturforschung C. A journal of biosciences</title><addtitle>Z Naturforsch C</addtitle><description>The methanol extract of the dried ripe fruits of Alpinia rafflesiana was investigated for its DPPH free radical scavenger constituents. 2′,3′,4′,6′-Tetrahydroxychalcone (7), which has never been isolated from natural sources was found to be most active as a DPPH free radical scavenger with the IC
value of 55 μᴍ. Other known compounds isolated from this species include 5,6-dehydrokawain (1), flavokawin B (2), 1,7-diphenyl-5-hydroxy-6-hepten-3-one (3), (-)-pinocembrin (4), cardamonin (5) and (-)-pinostrobin (6). The DPPH free radical scavenger compounds were detected using TLC autographic analysis. The percentage inhibition of DPPH free radical scavenging activity was measured on isolates (5-7) using colorimetric analysis.</description><subject>2′,3′,4′,6′-Tetrahydroxychalcone</subject><subject>Alpinia - chemistry</subject><subject>Alpinia rafflesiana</subject><subject>Biphenyl Compounds - isolation & purification</subject><subject>Biphenyl Compounds - pharmacology</subject><subject>Chalcones - chemistry</subject><subject>Chalcones - isolation & purification</subject><subject>Free Radical Scavenger Activity</subject><subject>Free Radical Scavengers - isolation & purification</subject><subject>Free Radical Scavengers - pharmacology</subject><subject>Hydrazines - isolation & purification</subject><subject>Hydrazines - pharmacology</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Malaysia</subject><subject>Models, Molecular</subject><subject>Molecular Structure</subject><subject>Picrates</subject><subject>Seeds - chemistry</subject><subject>Spectroscopy, Fourier Transform Infrared</subject><issn>0939-5075</issn><issn>1865-7125</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE1v1DAQhq0K1C6ld07IJwSHLHb8keTYLpQiVaICqkq9WI493rp1nK2dAOXX42VX4sRpZqTnfaV5EHpFyZIKKt7_jqaqCeEVpRWtSXuAFrSVompoLZ6hBelYVwnSiCP0Iud7QpgUjThER1RIKQXrFih8uLq6wOcJAH_V1hsd8Dejf0BcQ8KrcdiMEeKUsUvjgKc7KOjsyz06fBo2PnqNk3YuQPY6anyjQ1hi-LXEZ_phid_e-rj2PSRtQMO7l-i50yHDyX4eo-vzj99XF9Xll0-fV6eXlWFdO1XAbctc53Qvhe6BCmNFIx10dWst77kxQhLGOks44wDSuNaWoBUgeFtIdoze7Ho3aXycIU9q8NlACDrCOGclm5pJzusCkh1o0phzAqc2yQ86PSlK1NawKobV1rCiVG0Nl8jrfffcD2D_BfZKC3C2A37qMEGysE7zU1nU_TinWN7-b7fo_i4tpewPJxeL_A</recordid><startdate>20041101</startdate><enddate>20041101</enddate><creator>Mohamad, Habsah</creator><creator>Abas, Faridah</creator><creator>Permana, Dharma</creator><creator>Lajis, Nordin H.</creator><creator>Ali, Abdul Manaf</creator><creator>Sukari, Mohd Aspollah</creator><creator>Hin, Taufiq Y. Y.</creator><creator>Kikuzaki, Hiroe</creator><creator>Nakatani, Nobuji</creator><general>Verlag der Zeitschrift für Naturforschung</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20041101</creationdate><title>DPPH Free Radical Scavenger Components from the Fruits of Alpinia rafflesiana Wall. ex. Bak. (Zingiberaceae)</title><author>Mohamad, Habsah ; Abas, Faridah ; Permana, Dharma ; Lajis, Nordin H. ; Ali, Abdul Manaf ; Sukari, Mohd Aspollah ; Hin, Taufiq Y. 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Y.</creatorcontrib><creatorcontrib>Kikuzaki, Hiroe</creatorcontrib><creatorcontrib>Nakatani, Nobuji</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Zeitschrift für Naturforschung C. A journal of biosciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mohamad, Habsah</au><au>Abas, Faridah</au><au>Permana, Dharma</au><au>Lajis, Nordin H.</au><au>Ali, Abdul Manaf</au><au>Sukari, Mohd Aspollah</au><au>Hin, Taufiq Y. Y.</au><au>Kikuzaki, Hiroe</au><au>Nakatani, Nobuji</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>DPPH Free Radical Scavenger Components from the Fruits of Alpinia rafflesiana Wall. ex. Bak. 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value of 55 μᴍ. Other known compounds isolated from this species include 5,6-dehydrokawain (1), flavokawin B (2), 1,7-diphenyl-5-hydroxy-6-hepten-3-one (3), (-)-pinocembrin (4), cardamonin (5) and (-)-pinostrobin (6). The DPPH free radical scavenger compounds were detected using TLC autographic analysis. The percentage inhibition of DPPH free radical scavenging activity was measured on isolates (5-7) using colorimetric analysis.</abstract><cop>Germany</cop><pub>Verlag der Zeitschrift für Naturforschung</pub><pmid>15666539</pmid><doi>10.1515/znc-2004-11-1208</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | 2′,3′,4′,6′-Tetrahydroxychalcone Alpinia - chemistry Alpinia rafflesiana Biphenyl Compounds - isolation & purification Biphenyl Compounds - pharmacology Chalcones - chemistry Chalcones - isolation & purification Free Radical Scavenger Activity Free Radical Scavengers - isolation & purification Free Radical Scavengers - pharmacology Hydrazines - isolation & purification Hydrazines - pharmacology Magnetic Resonance Spectroscopy Malaysia Models, Molecular Molecular Structure Picrates Seeds - chemistry Spectroscopy, Fourier Transform Infrared |
| title | DPPH Free Radical Scavenger Components from the Fruits of Alpinia rafflesiana Wall. ex. Bak. (Zingiberaceae) |
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