Inhibition of caspase-3 blocks long-term potentiation in hippocampal slices

Incubation of rat hippocampal slices with the specific caspase-3 inhibitor Z-DEVD-FMK led to suppression of long-term potentiation (LTP), which developed over a period of time. Incubation of Z-DEVD-FMK for 4 h and more prevented tetanization from evoking LTP; Z-DEVD-FMK had no effect on baseline mea...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience and behavioral physiology 2004-11, Vol.34 (9), p.877-880
Hauptverfasser:	Kudryashov, I E, Yakovlev, A A, Kudryashova, I V, Gulyaeva, N V
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Caspase 3 Caspase Inhibitors Caspases - physiology Electric Stimulation - methods Hippocampus - drug effects Hippocampus - physiology Hippocampus - radiation effects In Vitro Techniques Long-Term Potentiation - drug effects Long-Term Potentiation - physiology Long-Term Potentiation - radiation effects Oligopeptides - pharmacology Rats Rats, Wistar Regression Analysis Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!