Long-Term Small Molecule and Protein Elution from TiO2 Nanotubes

In this study, TiO2 nanotubes of various dimensions were used to elute albumin, a large protein molecule, as well as sirolimus and paclitaxel, common small molecule drugs. The nanotubes controlled small molecule diffusion for weeks and large molecule diffusion for a month. Drug eluted from the nanot...

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Veröffentlicht in:	Nano letters 2009-05, Vol.9 (5), p.1932-1936
Hauptverfasser:	Peng, Lily, Mendelsohn, Adam D, LaTempa, Thomas J, Yoriya, Sorachon, Grimes, Craig A, Desai, Tejal A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - chemistry Cell Line Cell Proliferation Drug Implants - chemistry Mice Nanotubes - chemistry Paclitaxel - chemistry Pharmaceutical Preparations - chemistry Proteins - chemistry Serum Albumin, Bovine - chemistry Sirolimus - chemistry Titanium - chemistry
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